Measles Outbreak, Fake News and Mass Hysteria
by Jeffrey Dach MD
Darla Shine, Wife of a Trump Administration Official, found herself labeled as “anti-vaccination” in the center of a media storm this week after she made a few comments on social media about “bringing back childhood diseases” like measles, . (1-7)(27)
Virtually every major news outlet ran vicious anti-Darla Shine “hit-piece” articles which defamed her character, her husband’s character, and offered opposing “Pro-Vaccination Material” for the discerning consumer. Header image: Measles virus diagram and Electron Microscopy courtesy of Human Viruses. Measles is an RNA virus,
Search Engine Results Couldn’t Be Rigged, Could They ?
In addition, Google search engine results have obviously been manipulated to preferentially show pro-vaccination search results when entering key words such as “Darla Shine” and “measles”. Welcome to the new world of internet censorship. Next you might ask: will You-Tube and Facebook block users who question vaccine safety? If vaccines are so safe and effective, why did Congress have to grant immunity from liability to the vaccine makers in 1986? And why does the Federal Vaccine Court keep paying out Billions of dollars in compensation for vaccine injuries?
Primary and Secondary Vaccine Failure- About 9 Per cent
Of course, we can expect a measles outbreak every year or so, simply because measles vaccine immunity wanes gradually over time, rendering the vaccinated population susceptible to wild type measles infection.(8) For example, Dr Gregory Poland, world expert on measles vaccine, wrote an article in Vaccine 2012, saying measles outbreaks in highly vaccinated populations occur because of primary and secondary vaccine failure.(36)
“Thus, measles outbreaks also occur even among highly vaccinated populations because of primary and secondary vaccine failure, which results in gradually larger pools of susceptible persons and outbreaks once measles is introduced . This leads to a paradoxical situation whereby measles in highly immunized societies occurs primarily among those previously immunized” .(Quote Gregory Poland)(36)
Similar measles outbreaks have been documented in other highly vaccinated populations in other countries such as Israel(9), Nigeria (10), Korea(22), Czech Republic (23), Australia (24), and Japan (25) involving the vaccinated as well as unvaccinated. (9,10)(22-25)
In the United States, vaccine failure is estimated to be about 9%. From 2012-2014, roughly 9% of measles cases occurred in fully vaccinated individuals.(85)
Well documented cases of secondary vaccine failure have been reported in fully vaccinated health care workers. A (2-dose) fully vaccinated 30 year old female doctor exhibited measles rash and fever after exposure to a 17 year old patient with measles.(83) The doctor tested positive for measles virus RNA as well as measles antibodies.(83)
Longer Term Protection with Wild Type Measles
Dr Jan Smeta says in 2017 PLOS, that natural infection with wild type measles confers longer term protection than live measles vaccine, and vaccine immunity wanes gradually over time. Mother’s who had wild type measles may pass antibody protection to the newborns, however, mothers who had the live attenuated measles vaccine can not do so. Their babies are unprotected.(23)
“coverage against measles, which in the Czech Republic, over the long term, exceeds 95%…Natural infection provides longer term protection than vaccination. Post vaccination immunity decreases in time. Passive immunity may be compromised in newborns of vaccinated mothers.”(23)
As Dr Poland mentions, if the problem is vaccine failure, then the solution is to design a better vaccine, not to remove the religious and philosophical vaccine exemptions by legislative mandate. Removing vaccine exemptions does not address the issue of primary and secondary vaccine failure which is responsible for recurring outbreaks even in highly vaccinated populations.
Whipping Up Hysteria and Fear to Remove Exemptions
However, in spite of this obvious problem of measles vaccine failure, the media is whipping up measles hysteria to push for legislation to remove vaccine exemptions. Fear makes people surrender their constitutional right to medical freedom, reluctantly agreeing to be coerced into medical procedures they would otherwise decline.
Conspiracy Theory ?
Of course, the media is merely trumpeting the Pro-Vaccine agenda of Big Pharma. That is a given, and to be expected. However, call it a conspiracy theory, but isn’t it a little bit suspicious that the push for vaccine mandates is orchestrated by the Big Pharma vaccine makers who contribute heavily to state congressional bodies. Isn’t it a bit suspicious that Big Pharma stands to pocket billions from their vaccines, with no incentive to make them safe, since Big Pharma was removed from liability in 1986 by The National Childhood Vaccine Injury Act (NCVIA). Isn’t is it a bit suspicious that vaccines are not required to undergo the same type of placebo controlled trials as all other drugs ? Isn’t is it a bit suspicious that vaccine makers are exempt from liability for vaccine adverse side effects? Instead, the vaccine damaged child must seek compensation in the federal vaccine court, fighting for years against a team of adversarial federal attorneys.
Adverse Effects of Measles Vaccine
This is a good place to ask the question, how safe is the attenuated live virus measles vaccine? This brings up the question of reported adverse events. Here is a quote from the NVIC (National Vaccine Information center)
“As of November 30, 2018, there have been more than 92,844 reports of measles vaccine reactions, hospitalizations, injuries and deaths following measles vaccinations made to the federal Vaccine Adverse Events Reporting System (VAERS), including 457 related deaths, 6,902 hospitalizations, and 1,736 related disabilities.”(28)
Deaths: 2 measles vs. 127 vaccine
According to Dr Alvin Moss, there have been 2 deaths linked to wild type measles in the last 15 years, yet there here have been 127 deaths linked to the measles vaccine.(29) Dr. Alvin H. Moss, M.D. testified at the West Virginia Senate Education Committee on Saturday, March 18, 2017. Dr. Moss is a physician and professor in the Center for Health Ethics & Law department at West Virginia University. Jump to very end of video where Dr Moss discusses 2 reported deaths from measles compared to 127 reported deaths from measles vaccine (reported in VAERS) during same time period.(29)
If you accept Dr Alvin Moss’s statistics, then the live measles vaccine is responsible for 63.5 times more deaths than the wild type measles virus. It doesn’t take a rocket scientist to figure this out. The risk/benefit ratio comes out in favor of the wild type virus, not the vaccine.
Live Polio Vaccine Discontinued
This same thing happened with the live polio vaccine which was discontinued (in the US) in 2000 because the vaccine was causing more cases of polio than the wild type polio virus itself.(37) Perhaps it is time to think about discontinuing the live attenuated measles vaccine for this same reason. The CDC declared measles eradicated in the year 2000. If the measles vaccine is causing 63.5 more deaths than the wild type measles virus, why not just declare victory and stop vaccinating for measles?
One problem with the idea of simply stopping measles vaccination is that the current measles vaccination program has created a large population if at-risk infants of vaccinated mothers who have a lower level of measles antibody. These infants are more at risk for measles complications compared to the infants of non-vaccinated mothers with previous wild-type measles infection. Perhaps the outcome of cessation of a nation wide measles vaccination program can be predicted by examination of measles epidemics in unvaccinated communities such as the Orthodox Protestant Community of the Netherlands.
Measles Epidemics in Unvaccinated Communities
The Orthodox Protestant Community in Netherlands is a tight knit, largely unvaccinated community and therefore susceptible to periodic measles epidemics, the subject of a number of medical studies.(60) Comparing two epidemics, one in 1999, and the other in 2013, Dr Tom Woudenberg reports the incidence of measles in infants less than 6 months of age was higher in the later epidemic because children born to vaccinated mothers received lower levels of antibody protection from their mothers (through maternal transmission) compared to un-vaccinated mothers (who had experienced a wild type measles infection years before). These un-vaccinated mothers had higher measles antibody titers which protected the child via maternal transmission.
“The incidence (of measles) in infants aged less than 6 months was higher in 2013–2014 than in the 1999–2000 epidemic. This is likely to be related to the lower level of maternal antibodies in children born to vaccinated mothers compared with children born to unvaccinated mothers .”(60)
Comparing Measles Associated Complications in Unvaccinated Communities to the Measles Vaccine Associated Complications
We have the VAERS (Vaccine Adverse Event Reporting System) for measles vaccine adverse events and complications which can be compared to the complications found in measles epidemics in un-vaccinated communities. However, we really need a prospective controlled study comparing the vaccinated to the un-vaccinated group. This type of study can be done in a largely unvaccinated community such as the Orthodox Protestant in the Netherlands. Amazingly, this study has never been done. So we don’t know which group has more complications, the wild type measles group, or the measles vaccinated group.
Vaccine Strain Measles- Measles Caused by the Vaccine
Since the measles vaccine is a live virus vaccine, vaccination itself may cause a disease indistinguishable from measles, with shedding of vaccine strain virus.(11) (31,32) In these cases , the exact strain of virus can be identified using real time PCR (polymerase chain reaction). When this PCR testing was carried out on samples obtained from the 2015 California Disney measles outbreak, 73 of 194 cases (37.6%) were found to be vaccine strain measles in children recently vaccinated. Dr Felicia Roy says in a 2017 article in Journal of Clinical Microbiology: (62)
“During the measles outbreak in California in 2015, a large number of suspected cases occurred in recent vaccinees (3). Of the 194 measles virus sequences obtained in the United States in 2015, 73 were identified as vaccine sequences (R. J.McNall, unpublished data).”(62-63)
Many of the “California Disney Measles Epidemic” were in fact, measles caused by the measles vaccine itself. This information is not widely known, and since it was never revealed in the mainstream media.
In response to the hysteria whipped up over the “Disney measles epidemic” State Senators Richard Pan (D-Sacramento) and Ben Allen (D-Santa Monica) introduced SB 277, later signed into law by Governor Brown eliminating personal and religious vaccine exemptions. None of these trusted state government officials were informed that passing totalitarian legislation to remove vaccine exemptions does nothing to reduce the Disney measles cases caused by the vaccine itself, representing approximately 40% of the total cases.
Measles Vaccine Encephalitis
In 1999, Dr Ari Bitnun reported a case of a child who died after a measles vaccination from “Measles inclusion body encephalitis”. This child’s illness was caused by vaccine strain virus as confirmed with RNA sequencing of the virus particle.(35)
“We report a case of measles inclusion-body encephalitis in an apparently healthy 21-month-old boy 8.5 months after measles-mumps-rubella vaccination. He had no prior evidence of immune deficiency and no history of measles exposure or clinical disease. . . . The nucleotide sequence in the nucleoprotein and fusion gene regions was identical to that of the Moraten and Schwarz vaccine strains. . . . On hospital day 51, the patient died after ventilatory support was withdrawn. . . . An immunologic evaluation of this patient was prompted by the diagnosis of MIBE. ”(35)
Although the measles vaccine may cause an illness indistinguishable from wild type measles, there has never been a documented case of measles vaccine strain virus transmissible from one human to another human.(12) Vaccine strain measles virus shedding from vaccinated individuals has been demonstrated, however this has never resulted in clinical case of measles in a contact. The vaccine virus has been attenuated which prevents transmission from one human to another.(12)
Eradication of Wild Type Measles Virus with Vaccine ?
At the highest level of the scientific community of measles vaccine experts, it is now generally regarded that eradication of wild type measles virus even in highly vaccinated communities is impossible.(65-69)(80-82) The reason for this is: Wild type measles virus circulates among vaccinated individuals who are in fact, asymptomatic carriers.(65-69)(80-82) Unlike vaccine strain measles virus which can not be transmitted to contacts, wild type measles virus can be transmitted from asymptomatic previously vaccinated carriers to the unvaccinated, thus causing measles outbreaks in unvaccinated ethnic communities as well as two groups of susceptible individuals in the fully vaccinated population. These two susceptible groups in the vaccinated population, as mentioned above, are those who have either primary or secondary vaccine failure, and unprotected young infants who have not had the benefit of maternal antibody transmission.
Blaming the Non-Vaccinated for Measles Outbreaks in Highly Vaccinated Populations ? illogical and Unfair
This is a quote from author James Lyons Weiler (with many references from the medical literature:
“vaccinated individuals can, and have always, been known to be able to be infected with wild-type measles virus. Since this is true, the rare non-vaccinated child is not, in a highly vaccinated population, to be the primary source of new transmissions of measles. Instead, the vaccinated individuals with subclinical infections may be driving new infections in schools. It is therefore illogical, and quite unfair, to blame unvaccinated individuals when infected asymptomatic individuals can go to school unabated.“(66) End Quote
The Unvaccinated Are a Dangerous Threat to Society by Preventing “Herd Immunity”
The mass media repeats over and over the argument that the unvaccinated are a threat the society. Their argument uses the mythical idea of “herd immunity“, an imaginary level of vaccine uptake which approaches 100% of the population which prevents outbreaks of infectious disease. In order to achieve “herd Immunity”, state legislative bodies must pass draconian legislation to eliminate vaccine exemptions and make vaccines mandatory. Mary Holland published an article in 2014 Oregon law review which examined the concept of herd immunity. (50-51) Dr Holland says herd immunity is unattainable in the real world, “public health policies have not attained herd immunity for any childhood disease despite sixty years of compulsory policies and intensive effort.”(51)
“Herd immunity is generally unattainable in the real world because key assumptions, like population homogeneity, do not exist and because current vaccine technology is imperfect. Vaccination programs should therefore aim to achieve herd effect, not herd immunity and concomitantly, disease control rather than eradication.
Because public health policies have not attained herd immunity for any childhood disease despite sixty years of compulsory policies and intensive effort, it seems both logical and wise to recalculate our policies. It is time to abandon the illusion of herd immunity through compulsion and to adopt realistic and respectful policies to achieve herd effect based on parents’ informed choices.”(51) endquote
Vaccinate for the Good of the Collective
Dr Lee Hieb has a different perspective in her article,”How vaccine hysteria could spark totalitarian nightmare “. She says this argument to vaccinate for the “Good of the Collective” is not only scientifically questionable(49), it is unethical:
“The argument that I must vaccinate my children for the good of the community is not only scientifically questionable, it is an unethical precept. It is the argument all dictators and totalitarians have used. “Comrade, you must work tirelessly for the good of the collective. You must give up your money and property for the good of the collective, and now … you must allow us to inject your children with what we deem is good for the collective.” If American’s don’t stand up against this, then we are lost. Because we have lost ownership of ourselves. Our bodies are no longer solely ours – we and our children are able to be commandeered for the “greater good.”endquote.(48)
Steven Lantier, M.D., an anesthesiologist from Oklahoma says, “Mandatory vaccines are bad medicine, bad politics”. (49) He says:
“The people who are asking for exemptions from vaccinations have good science behind them. On this topic, I say let the parents choose. Making vaccines mandatory is bad medicine and very bad politics.”
The Unvaccinated Are Not a Public Heath Risk
In an Open Letter to Legislators Currently Considering Vaccine Legislation from Tetyana Obukhanych, PhD in Immunology April 2015, she says:(52) She says:
“discrimination in a public school setting against children who are not vaccinated for reasons of conscience is completely unwarranted as the vaccine status of conscientious objectors poses no undue public health risk.”(52)
Rockland County Bans Unvaccinated Students from Class
A Federal judge ruled in favor of Rockland County officials who issued a ban order for unvaccinated students throughout the county unless vaccination rates at their school reached 95%.(71) 44 students at Green Meadow Elementary School had been out from school for 93 days, with no hope of returning soon. Mr. Michael Sussman, the lawyer for the 44 families, as well as a few family members made statements to the press at the courthouse steps. (70) If a student comes down with a case of a measles with fever and rash, they will be quarantined and are not a threat. This issue refers only to asymptomatic carriers who pick up measles at the mall or some other place away from school, feel well, and do not appear sick and then go to school posing a threat to others.
Previously Immunized Commonly Have Asymptomatic Wild Type Measles Infection
Detection of wild type measles RNA in lymphocytes of previously immunized children, bone marrow aspirates of adults, and on autopsy is commonly seen.(74-75)(80) This means that asymptomatic infection with wild type measles virus is quite common in previously immunized children, as well as adults. (74-75)(80)
In my opinion, deeming unvaccinated students a threat to others and banning unvaccinated students from school is discriminatory and does not serve the public interest or protect public health. Apparently the judge was unaware that unvaccinated students pose the same health threat as vaccinated students pose (if any). Both vaccinated as well as unvaccinated students may unknowingly pose as asymptomatic measles carriers, and therefore represent the same health threat to others.(67)(72)(74-76)
Since asymptomatic (wild type) measles virus infection has been documented in both unvaccinated as well as fully vaccinated children, both groups pose the same health threat as unknowing asymptomatic carriers. To ban one group and not the other, represents a form of discrimination. In addition, there are documented cases of fully vaccinated adults transmitting (wild type) measles infection to children.(67)(76)
The 2011 New York measles epidemic was reported by Jenifer Rosen in 2014, Clinical Infectious Disease.(67) This New York epidemic was started by a fully, twice vaccinated individual who then transmitted wild type measles to four other fully immunized New Yorkers with typical symptoms, confirmed by laboratory testing for measles PCR-RNA and antibodies.(67)
Using the same logic as the Rockland County Health Department, one must consider all adults in the school (janitors, teacher, administrators) to pose the same threat as unvaccinated students, as some adults may be posing as asymptomatic carriers. The final result is a completely empty school with no people inside, about as absurd as a Forrest Gump movie. Rockland County has succeeded in verifying Ronald Reagan’s famous quote: “The most terrifying words you will hear in the English language: I’m from the government and and I am here to help you”.
Although the measles cases were reported in the Orthodox Jewish community in Rockland county, there have been no reported cases of measles in the Green Meadow School or the immediate vicinity. Banning students from school is a form of quarantine warranted for sick students with symptomatic measles infection. All are in agreement with this. However, to ban unvaccinated students on the theoretical risk they pose a health threat as asymptomatic carrier is discriminatory, since as the medical literature shows, the fully vaccinated also pose a theoretical risk as asymptomatic carrier.(67)
Measles Titer Test Proves Immunity
Most older adults working in the Green Meadow school, teachers, janitors, administrators, are unvaccinated because they were born before the vaccine was introduced in 1963, and had measles infection in childhood which confers life long immunity to measles. However, the only way to prove these School Employee adults are immune and not a health threat to the students is to test them for neutralizing antibodies (titer test). This has not been done.
I Already Had Measles, So I Dont Need the Vaccine
For the unvaccinated children banned from attending school by the Rockland County Health Department, one recourse is to get tested for neutralizing antibodies. For those children who had previously had wild type measles, the titer test will show elevated neutralizing antibodies, proving the child has complete immunity conferred by previous measles infection.(85) Now, when the classmates accuse the child of being a “leper”, or an asymptomatic measles carrier, they can reply they are exempt from measles vaccination and are not a threat because of previous measles infection which has conferred life long immunity to the disease.
Never had measles, so not doing the titer test?
Do the test anyway since some children may have had a case of only mildly symptomatic measles which may have been missed, and have positive titers now. Most schools and health departments accept a positive titer test for neutralizing measles antibodies as proof of immunity which allows entry to school. Remember vitamin A and C for those wishing to prevent or reduce complications from measles infection. This is discussed below.
Looking for Help? Dept. of Justice “Task Force on Religious Liberty”
To ban one group of students (the unvaccinated with religious exemptions) while not banning the other (the vaccinated) may qualify as a form of religious discrimination.
For those who wish to enlist help from higher up, the Department of Justice Task Force on Religious Liberty is the place to ask. Their mission is to protect religious liberties by preventing county or state agencies from trampling over religious rights such as religious exemptions from vaccinations.
Banning unvaccinated students is discriminatory because they pose the same threat as fully vaccinated students who may, in fact, pose unknowingly as asymptomatic carriers.(65-69)(72) If these unvaccinated students are exercising their religious freedom to claim a religious exemption, then banning them is a form of religious discrimination.(i.e. Perhaps these families take religious exception to the use of aborted fetal cell lines used to manufacture vaccines, as an example)
There is no guarantee this argument will work, and it is unknown whether the Task force on Religious Liberty will be interested in taking on the case. No harm in calling them to ask, though.
Religious Liberty Task Force is co-chaired by : Acting Associate Attorney General Jesse Panuccio, Principal Deputy Associate Attorney General, Office: (202) 514-9500 and Beth A. Williams, Assistant Attorney General for the Justice Department’s Office of Legal Policy: (202) 514-4601
The Case Against Removing Non-Medical Exemptions, Maine
A 14 year old High School Student from Maine, Colin Aponte of Blue Hill Bangor, Testifying in Opposition to Proposed Bill LD 798 to remove non-medical vaccine exemptions and in support of LD 987 to expand medical vaccine exemptions. He uses many of the same arguments listed above: Begin Quote Colin Aponte:
“1) Why unfairly single out unvaccinated students when vaccinated students may spread disease, too, if their immunity wanes or a blood titer shows they never developed immunity in the first place.
2) Why are you unfairly singling out kids, why aren’t you requiring every single adult in Maine to follow the CDC vaccine schedule in order to protect public health. (I would add here this is assuming the adult has lost immunity shown by blood titer testing)
3) What will happen to me as an unvaccinated kid? Will I be allowed out in public or quarantined at home? Will I be forced to wear a badge on my clothing to warn other people to stay away from me?
4) why can’t the law remain the same as it is now? Right now, if someone contracts a disease at school, unvaccinated kids have to stay home from school until the threat passes. This seems like the perfect compromise. It allows me the right to a public education, and keeps the spread of disease to a minimum. LD798 goes way too far. Under LD798, I will have no educational future in Maine. Please do not pass this bill.”Endquote
A Vaccine Expert MD Testimony in Maine
Dr. Meryl Nass opposes LD798 and supports LD987. Click Here for her testimony to the same committee in Maine: 3/13/19 testimony on vaccine exemptions to the Maine joint Education and Cultural Affairs Committee (92)
“The diseases that persist and have been in the news remain a challenge, simply because the vaccines have a high failure rate–not because of the unvaccinated.” End quote Dr Meryl Nass.
Houston, We Have a Problem
Pertussis (Whooping cough) Increasing In Spite of High Vaccine Coverage
Above image: Number of reported pertussis cases increasing in US 1922–2016. Red Circles show introduction points for three versions of (DTP) Pertussis Vaccine. Large red ellipse upper right: close up of increasing disease incidence. Courtesy of Dr Jennifer Liang 2018 FIGURE 1 (93)
Dr Jennifer Liang says in 2018 MMR (93) that waning immunity in spite of high vaccine coverage is the cause of increasing pertussis cases (whooping cough).(93)
“an increase in the number of reported pertussis cases among children and adolescents since the mid-2000s has been attributed to the waning of acellular pertussis vaccine-induced immunity.…Vaccination coverage with DTaP in children aged 19–35 months remains consistently high, at 95.0% for ≥3 DTaP doses.”(93) Endquote Jennifer Liang.
Mothers vaccinated for pertussis in childhood have waning immunity, with little or no maternal antibody transmission to protect their newborns. This has created a population of pertussis susceptible newborns with high rate of complications and death from the disease. “The highest percentage of pertussis-related hospitalizations and deaths occurs among infants aged <2 months “(93)
Pertussis Vaccine Makes Us More Susceptible to Disease, Not Less
According to Dr Cherry in a 2019 article in the Journal of Pediatric Infectious Disease, past mistakes made with the Pertussis vaccine have rendered the population MORE susceptible to disease, not LESS. (55) Regarding the Pertussis vaccine (also known as Whooping Cough), Dr Cherry says:
“In the last 13 years, major pertussis epidemics have occurred in the United States, and numerous studies have shown the deficiencies of DTaP vaccines, including the small number of antigens that the vaccines contain and the type of cellular immune response that they elicit. The type of cellular response a predominantly, T2 response (antibodies) results in less efficacy and shorter duration of protection. Because of the small number of antigens (3-5 in DTaP (acellular) vaccines vs >3000 in DTwP (whole cell) vaccines), linked-epitope suppression occurs. Because of linked-epitope suppression, all children who were primed by DTaP vaccines will be more susceptible to pertussis throughout their lifetimes, and there is no easy way to decrease this increased lifetime susceptibility.”(55)
Long Term Effects of Mass Vaccination Largely Unknown
Drs. Heffernan and Keeling in their 2009 article “Implication of vaccination and waning immunity,” wrote that the combination of waning vaccine induced immunity, and high levels of vaccine uptake creates susceptible populations even more at risk of “larger epidemics” than predicted.(53) They say:
“In particular, we show that moderate waning times (40–80 years) and high levels of vaccination (greater than 70%) can induce large-scale oscillations with substantial numbers of symptomatic cases being generated at the peak. In addition, we predict that, after a long disease-free period, the introduction of infection will lead to far larger epidemics than that predicted by standard models. These results have clear implications for the long-term success of any vaccination campaign and highlight the need for a sound understanding of the immunological mechanisms of immunity and vaccination” (53).
Drs. Heffernan and Keeling write there is a “need for a sound understanding of the immunological mechanisms of immunity and vaccination.” The implication, of course. is that as of 2009, science does not have a sound understanding of immunologic mechanisms of immunity and vaccination. Does this sound like the science is settled? No it does not.
Wild Type Measles as Cancer Prevention ?
A number of studies suggest that having wild type measles (and other childhood illnesses) reduces the rate of various cancers later as an adult.(43,44) In addition, a number of cases reports in the medical literature show acute febrile measles infection may induce remission in various types of cancer.(13,14) This has spurred interest in developing an “oncolytic measles virus” as a potential cancer treatment.(15-18) Perhaps interest in the measles virus as an anticancer treatment has been stimulated by success in Latvia with the Rigvir ECHO-7 enterovirus approved for treatment of melanoma.(45-47)
Vitamin A and Vitamin C for Measles
Vitamin A deficiency is associated with mortality from measles, and most serious measles cases are preventable with adequate levels of vitamin A. (38) (19) You might think while bashing Darla Shine, CNN or Newsweek would mention the importance of Vitamin A supplementation to help with rapid recovery (without complications) from the wild measles virus and from the vaccine strain virus. You would think that in addition to banning unvaccinated students, the Rockland County Health department might issue an advisory about vitamin C and Vitamin A. None of them mentioned it.
For those individuals who wish to minimize risk of complication from measles infection, supplemental Vitamin C and Vitamin A has been studied and shown helpful. Thomas Levy MD’s book, “Curing the Incurable: Vitamin C, Infectious Diseases and Toxins” discusses the benefits of supplemental vitamin A and vitamin C for viral illness.
“Like polio and hepatitis, measles is one more disease that is completely curable by properly dosed Vitamin C given by the proper route. Also, when adequate dosages are ingested regularly, measles can also be prevented. Other vitamin supplementation is also a good idea. Goskowitz and Eichenfeld (1993) noted that an acute Vitamin A deficiency can be seen in children with measles, usually associated with a more severe disease. However, because Vitamin C can promptly cure a fully developed case of measles, the ability to prevent an infection is not nearly so important. In fact, a valid argument can be made that contracting the disease, curing it with Vitamin C, and then attaining the resultant long-term immunity to the disease might be the most desirable way to proceed. This is especially true since adequate Vitamin C may not always be readily available and/or there may not be a doctor willing to dose it properly when the disease strikes.” Endquote Dr Thomas Levy (86)
Conclusion: The Medical Information War is in Full Gear. Which side will you be on? The side of the “Sheeple”, succumbing to mass media hysteria, and surrendering your right to medical freedom? Or the side of “Constitutional Free Choice”, reserving your right to choose of your own free will?
Arizona Expands Vaccine Exemptions Amid Measles Outbreak
Amazingly, Arizona has stood up for medical freedom and against medical tyranny. Bravo for the brave state of Arizona!
Update 2/24/19: Arizona House Panel Votes to Expand Vaccine Exemptions Amid Ongoing Measles Outbreak by Catie Keck GizModo 2/24/19 . “the state House Health and Human Services Committee approved three bills with 5-4 votes and support from Republican lawmakers. Representative Nancy Barto, who sponsored the bills, claimed that the bills aim to “strike that balance” between arguments on “both sides” and that vaccinations are “not a one size fits all option for every child.” The aims of the bills include expanded exemptions for religious reasons as well as axing a requirement that parents or guardians sign a document in order to opt out of vaccinations.”endquote.
Debunking Measles Mania Interview with Dr Bob Sears on High Wire
Articles with related interest:
Jeffrey Dach MD
7450 Griffin Road Suite 190
Davie, Florida 33314
1) Wife of White House communications director pushes false anti-vaccination claims By Kate Sullivan, Debra Goldschmidt and Ben Tinker, CNN
2) Darla Shine, Wife of Top Trump Official Bill Shine, Goes on Pro-Measles, Anti-Vax Rant ‘Bring back our #ChildhoodDiseases,’ wrote the former Fox News executive’s wife, ‘they keep you healthy & fight cancer.’ Surprise: she’s dangerously wrong.
Tanya Basu 12:16 PM ET
3) Wife of Trump Aide Criticizes CNN Coverage of Measles Outbreak as ‘Fake Hysteria’ in Anti-Vaccination Message By Jenni Fink On 2/13/19 at 12:20 PM
4) Wife of White House communications chief goes on anti-vaccine tirade Former TV producer Darla Shine spreads conspiracy theories about measles outbreak on Sabrina Siddiqui Wed 13 Feb 2019 21.31 EST
5) Wife of Trump Administration Official Claims Measles Can Cure Cancer by Katie Herzog • Feb 13, 2019 at 11:34 am
by Katie Herzog • Feb 13, 2019 at 11:34 am
7) Wife of Trump Aide Criticizes CNN Coverage of Measles Outbreak as ‘Fake Hysteria’ in Anti-Vaccination Message By Jenni Fink On 2/13/19 at 12:20 PM
Mass vaccination can stop endemic disease outbreaks by removing wild virus transmission and circulation in the community, but does NOT induce permanent immunity in the vaccinated. It is well known and agreed upon, that because the measles vaccine gives a subclinical case of measles by injection, that the vaccine interrupted wild measles transmission. That is why we have low levels of wild measles today. The same applies to the oral poliovirus vaccine, which also carried enough risk so as to be discontinued in the USA.
Today with two measles vaccines to over 95% of the USA children and repeat vaccines later in life, we are left with:
Vaccinated mothers who do not protect their young infants like naturally immune mothers did, and thus a MORE vulnerable infant population. A number of susceptibles in highly vaccinated populations that far exceeds the number of adolescent and adult susceptibles in the pre-vaccine era.
Why? Because of primary and secondary vaccine failure; something that prominent vaccinologists write about.
Today the measles outbreaks in the USA are blamed on the vaccine refusers, despite the fact that half of the cases from the California Disneyland outbreak were of “unknown” vaccination status and 18% were fully vaccinated.
A paper from 2011 by Shi looked to see the genetic variation in wild type measles viruses and they found it is becoming significant enough to be thinking of the “new golden era of vaccines” and to ramp up the current vaccines and bring in some new ones in order to get around the growing problem of antigenic drift among highly vaccinated populations.
Shi came right out and said of the 14 out of 16 cases that were fully vaccinated who were tested:
“These data suggest that the 16 patients from whom the 16 measles strains were isolated were susceptible to wild-type measles virus infection, perhaps resulting from the mutations of the wild-type measles virus.”
Today, all clinical cases of measles in vaccinated people are genotyped, and if the virus in the infected person is a vaccine virus, that case is struck from the record.
measles mortality had declined by over 98% in the United States by the time the first vaccine was introduced
9) Avramovich E, Indenbaum V, Haber M, et al. Measles Outbreak in a Highly Vaccinated Population — Israel, July–August 2017. MMWR Morb Mortal Wkly Rep 2018;67:1186–1188.
On August 6, 2017, the Israeli Defense Force Public Heath Branch (IDFPHB) was notified of two suspected measles cases. IDFPHB conducted an epidemiologic investigation, which identified nine measles cases in a population with high measles vaccination coverage. All measles patients had signs and symptoms consistent with modified measles (i.e., less severe disease with milder rash, fever, or both, with or without other mild typical measles symptoms).
No quarantine was recommended for contacts.
10) Faneye, Adedayo O., et al. “Measles virus infection among vaccinated and unvaccinated children in Nigeria.” Viral immunology 28.6 (2015): 304-308.
This study investigated measles infection in vaccinated and unvaccinated children presenting with fever and maculopapular rash during measles outbreaks in the southern and western states of Nigeria. Measles, an acute viral illness caused by a virus in the family Paramyxoviridae, is a vaccine-preventable disease. Measles outbreak is common in Nigeria, despite the national immunization program. Children presenting with symptoms of measles infection in general hospitals and health centers in the states of southern and western Nigeria were recruited for this study. Vaccination history, clinical details, and 5 mL of blood were obtained from the children. Their sera samples were screened for specific immunoglobulin M antibodies to measles virus. Of 234 children tested (124 [53.2%] female), 133 (56.8%) had previously been vaccinated against measles virus, while 93 (39.7%) had not been vaccinated. Vaccination information for eight children could not be retrieved. One hundred and forty-three (62.4%) had measles IgM antibodies. Of these, 79 (55.3%) had been vaccinated for measles, while 65 (44.7%) had not. Despite the ongoing vaccination program in Nigeria, a high number of children are still being infected with measles, despite their vaccination status. Therefore, there is need to identify the reason for the low level of vaccine protection.
11) Rizzuti, Francesco A., and Joseph Kim. “Vaccine-associated measles in a healthy 40-year-old woman.” Canadian Medical Association. Journal 190.35 (2018): E1046-E1048.
12) Greenwood, Kathryn P., et al. “A systematic review of human-to-human transmission of measles vaccine virus.” Vaccine 34.23 (2016): 2531-2536.
Measles is one of the most contagious human diseases. Administration of the live attenuated measles vaccine has substantially reduced childhood mortality and morbidity since its licensure in 1963. The live but attenuated form of the vaccine describes a virus poorly adapted to replicating in human tissue, but with a replication yield sufficient to elicit an immune response for long-term protection. Given the high transmissibility of the wild-type virus and that transmission of other live vaccine viruses has been documented, we conducted a systematic review to establish if there is any evidence of human-to-human transmission of the live attenuated measles vaccine virus. We reviewed 773 articles for genotypic confirmation of a vaccine virus transmitted from a recently vaccinated individual to a susceptible close contact. No evidence of human-to-human transmission of the measles vaccine virus has been reported amongst the thousands of clinical samples genotyped during outbreaks or endemic transmission and individual case studies worldwide.
13) Msaouel, Pavlos, et al. “Oncolytic measles virus strains as novel anticancer agents.” Expert opinion on biological therapy 13.4 (2013): 483-502.
A number of published clinical reports throughout the 20th century have indicated the anticancer potential of wild type measles virus (MV) strains. The first such case was published in 1949 and reported Hodgkin’s lymphoma regression following wild-type measles infection . This was followed by multiple case reports describing significant regressions of hematological malignancies, including Burkitt’s lymphoma, Hodgkin’s disease and leukemias, occurring after natural infection with wild-type MV [3-10].
14) Mota, H. Carmona. “Infantile Hodgkin’s disease: remission after measles.” British medical journal 2.5863 (1973): 421. 2 year old lymphoma mass in neck disappears after measles case report
15) Russell, Stephen J., and Kah Whye Peng. “Measles virus for cancer therapy.” Measles. Springer, Berlin, Heidelberg, 2009. 213-241.
16) Msaouel, Pavlos, Angela Dispenzieri, and Evanthia Galanis. “Clinical testing of engineered oncolytic measles virus strains in the treatment of cancer: an overview.” Current opinion in molecular therapeutics 11.1 (2009): 43.
17) Lech, Patrycja J., and Stephen J. Russell. “Use of attenuated paramyxoviruses for cancer therapy.” Expert review of vaccines 9.11 (2010): 1275-1302.
18) Ong, Hooi Tin, et al. “Oncolytic measles virus targets high CD46 expression on multiple myeloma cells.” Experimental hematology 34.6 (2006): 713-720.
19) Measles Physicians for Informed Content
it has been scientifically confirmed that low levels of vitamin A are associated with measles mortality. Indeed, populations with prevalent vitamin A deficiency are 30–60 times more likely to die from measles.
Does measles cause more harm than the MMR vaccine?
The answer to this question is not known. In the pre-vaccine era, measles caused 400 annual cases of death and 100 annual cases of permanent harm; however, most serious measles cases are preventable with adequate levels of vitamin A. In contrast, the MMR vaccine causes 5,700 annual seizures, of which 300 (5%) result in epilepsy; and seizures are only 12% of the serious reactions from the MMR vaccine that are reported to VAERS. Furthermore, the Measles Vaccine Risk Statement (VRS) also shows that studies have not ruled out the possibility of MMR causing permanent harm four times more often than measles causes death.
The available research and data have not proven that the risks of the MMR vaccine are less than the risks of measles, as described in the Measles DIS and VRS.
20) Did vaccines save humanity?
BY J.B. HANDLEY August 3, 2018
21) Herd Immunity”? A dishonest marketing gimmick
BY J.B. HANDLEY June 8, 2018
22) Kang, Hae Ji, et al. “An increasing, potentially measles-susceptible population over time after vaccination in Korea.” Vaccine 35.33 (2017): 4126-4132.
Despite high measles vaccination coverage by a successful national vaccination program, small outbreaks have occurred following the importation from other countries in recent years, even though the circulation of wild measles viruses in Korea has been stopped since 2010 , .
Such outbreaks have affected mostly unvaccinated people, but they also occurred in adolescents and young adults who had been previously vaccinated against measles , .
During 2010–2016 in Korea, 36.2% of individuals with confirmed measles infection were unvaccinated, 46.8% were vaccinated previously (10.5% with 1-dose, 36.2% with 2-dose), and vaccination information was not available for 17% of infected individuals (data not shown).
The existence of potential factors underlying vaccine failure, such as waning immunity, was suggested by data generated in previous studies on measles outbreaks in highly vaccinated populations , , , .
Several reports have warned that the susceptibility to measles infection may be rising because of waning vaccine-induced immunity over time after vaccination, in the absence of natural boosting by circulating measles viruses , . Our data showed good agreement between the incidence of measles and the susceptible age groups (adolescents and young adults) with measles seronegativity observed, suggesting the potential accumulation of measles-susceptible individuals in the population due to waning immunity, which may pose increased risk for measles outbreaks following measles importation from other endemic countries.
23) Smetana, Jan, et al. “Decreasing Seroprevalence of Measles Antibodies after Vaccination–Possible Gap in Measles Protection in Adults in the Czech Republic.” PloS one 12.1 (2017): e0170257.
coverage against measles, which in the Czech Republic, over the long term, exceeds 95%
Natural infection provides longer term protection than vaccination
Post vaccination immunity decreases in time
Passive immunity may be compromised in newborns of vaccinated mothers
Czech Republic in 2014, during which 186 laboratory confirmed cases were recorded . The most affected age group was formed by persons aged 34–44 years, which corresponds with our finding of the lowest seropositivity of IgG antibodies .
Conclusions Our results confirm the long-term persistence of high seropositivity rate after natural measles infection. By contrast, seropositivity after vaccination decreases over time. Similarly, the concentrations of specific antibodies in persons with history of measles persist for a longer time period and at a higher level than in vaccinated persons. It shows that natural infection provides better protection than vaccination.
measles might therefore become a disease that can occur more often even in countries with high levels of vaccination coverage, such as the Czech Republic, not only in unvaccinated children, but especially in the adult population.
24) Gidding, H. F., et al. “Declining measles antibodies in the era of elimination: Australia’s experience.” Vaccine 36.4 (2018): 507.
A number of countries with sustained measles control have now demonstrated that measles-specific IgG antibodies decline with time since vaccination.
25) Kinoshita, Ryo, and Hiroshi Nishiura. “Assessing age-dependent susceptibility to measles in Japan.” Vaccine 35.25 (2017): 3309-3317.
Routine vaccination against measles in Japan started in 1978. Whereas measles elimination was verified in 2015, multiple chains of measles transmission were observed in 2016. We aimed to reconstruct the age-dependent susceptibility to measles in Japan so that future vaccination strategies can be elucidated.
METHODS: An epidemiological model was used to quantify the age-dependent immune fraction using datasets of vaccination coverage and seroepidemiological survey. The second dose was interpreted in two different scenarios, i.e., booster and random shots. The effective reproduction number, the average number of secondary cases generated by a single infected individual, and the age at infection were explored using the age-dependent transmission model and the next generation matrix.
RESULTS: While the herd immunity threshold of measles likely ranges from 90% to 95%, assuming that the basic reproductive number ranges from 10 to 20, the estimated immune fraction in Japan was below those thresholds in 2016, despite the fact that the estimates were above 80% for all ages. If the second dose completely acted as the booster shot, a proportion immune above 90% was achieved only among those aged 5years or below in 2016. Alternatively, if the second dose was randomly distributed regardless of primary vaccination status, a proportion immune over 90% was achieved among those aged below 25years. The effective reproduction number was estimated to range from 1.50 to 3.01 and from 1.50 to 3.00, respectively, for scenarios 1 and 2 in 2016; if the current vaccination schedule were continued, the reproduction number is projected to range from 1.50 to 3.01 and 1.39 to 2.78, respectively, in 2025.
CONCLUSION: Japan continues to be prone to imported cases of measles. Supplementary vaccination among adults aged 20-49years would be effective if the chains of transmission continue to be observed in that age group.
Measles Data and Statistics
Measles in the United States, 2016*
•86 cases reported from 19 states;
•97% cases import-associated
•Of the 18 direct importations, 12 were U.S. residents, 6 were foreign visitors
•73% were outbreak-related
•Outbreaks ranged in size from 6 to 32 cases
•Cases among U.S. residents (N=55)
•18% unknown vaccination status•26% vaccinated
27) Bring back our #ChildHoodDiseases’: White House communications director’s wife criticizes vaccines. By Lindsey Bever February 14 at 4:01 PM
28) Measles Overview
As of November 30, 2018, there have been more than 92,844 reports of measles vaccine reactions, hospitalizations, injuries and deaths following measles vaccinations made to the federal Vaccine Adverse Events Reporting System (VAERS), including 457 related deaths, 6,902 hospitalizations, and 1,736 related disabilities.
Over 50% of those adverse events occurred in children three years old and under. As of January 2, 2019, there had been 1,258 claims filed in the federal Vaccine Injury Compensation Program (VICP) for injuries and deaths following MMR vaccination, including 82 deaths and 1,176 serious injuries.
Evidence has been published in the medical literature that vaccinated persons can get measles because either they do not respond to the vaccine or the vaccine’s efficacy wanes over time19 20 21 22 and vaccinated mothers do not transfer long lasting maternal antibodies to their infants to protect them in the first few months of life.23 24
Dr. Alvin H. Moss, M.D. | Full Testimony (West Virginia Senate Education Committee)
30) Measles Madness: Dr. Brian Hooker’s Statement to WA Legislators
Brian S. Hooker, PH.D., P.E.
SCIENCE ADVISER, FOCUS FOR HEALTH | BIO February 13, 2019
31) Murti, M., et al. “Case of vaccine-associated measles five weeks post-immunisation, British Columbia, Canada, October 2013.” Eurosurveillance 18.49 (2013): 20649.
32) Kaic, Bernard, et al. “Spotlight on measles 2010: excretion of vaccine strain measles virus in urine and pharyngeal secretions of a child with vaccine associated febrile rash illness, Croatia, March 2010.” Eurosurveillance 15.35 (2010): 19652.
33) The Story of Measles’ Sharp Decline by Marco Cáceres Published April 12, 2016 | Vaccination, History
34) First They Came for the Anti-Vaxxers By Bretigne Shaffer April 23, 2015
35) Bitnun, Ari, et al. “Measles inclusion-body encephalitis caused by the vaccine strain of measles virus.” Clinical infectious diseases 29.4 (1999): 855-861.Measles_encephalitis_vaccine_strain_Ari_Bitnun_Clinical_infectious_diseases_1999
21 month old dies from measles encephalitis after MMR shot. Measles_encephalitis_vaccine_strain_Ari_Bitnun_Clinical_infectious_diseases_1999 Bitnun, Ari, et al. “Measles inclusion-body encephalitis caused by the vaccine strain of measles virus.” Clinical infectious diseases 29.4 (1999): 855-861.
“We report a case of measles inclusion-body encephalitis in an apparently healthy 21-month-old boy 8.5 months after measles-mumps-rubella vaccination. He had no prior evidence of immune deficiency and no history of measles exposure or clinical disease. . . . The nucleotide sequence in the nucleoprotein and fusion gene regions was identical to that of the Moraten and Schwarz vaccine strains. . . . On hospital day 51, the patient died after ventilatory support was withdrawn. . . . An immunologic evaluation of this patient was prompted by the diagnosis of MIBE. While we cannot ascribe his condition to any classic immunodeficiency syndrome, our findings support the presence of a primary immunodeficiency”
36) Poland, Gregory A., and Robert M. Jacobson. “The re-emergence of measles in developed countries: time to develop the next-generation measles vaccines?.” Vaccine 30.2 (2012): 103.
Thus, measles outbreaks also occur even among highly vaccinated populations because of primary and secondary vaccine failure, which results in gradually larger pools of susceptible persons and outbreaks once measles is introduced . This leads to a paradoxical situation whereby measles in highly immunized societies occurs primarily among those previously immunized .
37) Mutant Strains Of Polio Vaccine Now Cause More Paralysis Than Wild Polio June 28, 2017 NPR Jason Beaubien
38) Sudfeld, Christopher R., Ann Marie Navar, and Neal A. Halsey. “Effectiveness of measles vaccination and vitamin A treatment.” International journal of epidemiology 39.suppl_1 (2010): i48-i55.
39) Obukhanych, Tetyana. “Herd Immunity: Myth or Reality?.” STATE OF IMMUNITY 9.6 (2014): 85. Obukhanych Tetyana Herd Immunity Myth or Reality STATE OF IMMUNITY 2014.
40) Obukhanych, Tetyana. “Herd Immunity: Can Mass Vaccination Achieve It?.” The biomedical belief that a vaccine-exempt child endangers the society by not contributing to herd immunity is preposterous, because vaccinating every single child by the required schedule cannot maintain the desired herd immunity anyway.
41) Fisher, Barbara Loe. “The Moral Right to Conscientious, Philosophical and Personal Belief Exemption to Vaccination.” National Vaccine Information Center (NVIC) (1997).
42) Lawrence Solomon: Vaccines can’t prevent measles outbreaks
Lawrence Solomon: Measles in highly immunized societies occurs primarily among those previously immunized
43) Montella, Maurizio, et al. “Do childhood diseases affect NHL and HL risk? A case-control study from northern and southern Italy.” Leukemia research 30.8 (2006): 917-922.
To investigate the association between non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), and exposure to childhood diseases, we analyzed an Italian case-control study that included 225 histologically-confirmed incident cases of NHL, 62 HL cases, and 504 controls. After adjusting for confounding factors, all examined childhood diseases were negatively associated with HL. Measles was negatively associated with NHL, particularly follicular B-cell NHL. Our findings provide additional support to the hypothesis that infections by most common childhood pathogens may protect against HL or, at least, be correlated with some other early exposure, which may lower the risk of HL in adulthood. In addition, our study shows that measles may provide a protective effect against NHL.
44) Becker, Nikolaus, et al. “Self‐reported history of infections and the risk of non‐Hodgkin lymphoma: An InterLymph pooled analysis.” International journal of cancer 131.10 (2012): 2342-2348
A self-reported history of measles or whooping cough was associated with an approximate 15% reduction in risk.
45) Alberts, Pēteris, et al. “The advent of oncolytic virotherapy in oncology: The Rigvir® story.” European journal of pharmacology 837 (2018): 117-126. ECHO-7 virus Rigvir enterovirus
46) Proboka, Guna, et al. “Melanoma unknown primary brain metastasis treatment with ECHO-7 oncolytic virus rigvir: a case report.” Frontiers in oncology 8 (2018): 43.
47) Russell, Luke, and Kah-Whye Peng. “The emerging role of oncolytic virus therapy against cancer.” Chinese clinical oncology 7.2 (2018).
This review discusses current clinical advancements in oncolytic viral therapy, with a focus on the viral platforms approved for clinical use and highlights the benefits each platform provides. Three oncolytic viruses (OVs), an echovirus, an adenovirus, and a herpes simplex-1 virus, have passed governmental regulatory approval in Latvia, China, and the USA and EU. Numerous other recombinant viruses from diverse families are in clinical testing in cancer patients and we highlight the design features of selected examples, including adenovirus, herpes simplex virus, measles virus, retrovirus, reovirus, vaccinia virus, vesicular stomatitis virus. Lastly, we provide thoughts on the path forward for this rapidly expanding field especially in combination with immune modulating drugs.
48) How vaccine hysteria could spark totalitarian nightmare Lee Hieb, M.D. 02/04/2015 The argument that I must vaccinate my children for the good of the community is not only scientifically questionable, it is an unethical precept. It is the argument all dictators and totalitarians have used. “Comrade, you must work tirelessly for the good of the collective. You must give up your money and property for the good of the collective, and now … you must allow us to inject your children with what we deem is good for the collective.” If American’s don’t stand up against this, then we are lost. Because we have lost ownership of ourselves. Our bodies are no longer solely ours – we and our children are able to be commandeered for the “greater good.”
49) Point of View: Mandatory vaccines are bad medicine, bad politics
By Steven Lantier, M.D. Published: Mon, December 10, 2018 NewsOK
50) January 23, 2019 Herd Immunity: A False Rationale for Vaccine Mandates the Children’s Health Defense Team
Holland and Zachary painstakingly show, illogical mandates and “imperfect vaccine technology” mean that “herd immunity does not exist and is not attainable.” Even one hundred percent vaccination “cannot reliably induce herd immunity.” Thus, herd immunity is a “weak rationale” to compel all vaccines for all children.
51) Holland, Mary, and Chase E. Zachary. “Herd immunity and compulsory childhood vaccination: does the theory justify the law.” Or. L. Rev. 93 (2014): 1. Herd immunity and compulsory childhood vaccination Holland Mary Chase Zachar Oregon Law Review 2014
52) An Open Letter to Legislators Currently Considering Vaccine Legislation from Tetyana Obukhanych, PhD in Immunology April 2015
“children who are not vaccinated for reasons of conscience is completely unwarranted as the vaccine status of conscientious objectors poses no undue public health risk.”
53) Heffernan JM, Keeling MJ, “Implication of vaccination and waning immunity,” Proc R. Soc. B 276, 2071-2080 (2009). Implications of vaccination and waning immunity Heffernan and Keeling Proc Royal Soc Biol Sci 2009
In particular, we show that moderate waning times (40–80 years) and high levels of vaccination (greater than 70%) can induce large-scale oscillations with substantial numbers of symptomatic cases being generated at the peak. In addition, we predict that, after a long disease-free period, the introduction of infection will lead to far larger epidemics than that predicted by standard models. These results have clear implications for the long-term success of any vaccination campaign and highlight the need for a sound understanding of the immunological mechanisms of immunity and vaccination
54) VCC Responds to Measles Hysteria
February 21, 2019 By Vaccine Choice Canada
Ted Kuntz, Parent of a Vaccine Injured Child now deceased
Vice President – Vaccine Choice Canada
55) Cherry JD1. The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future.J Pediatric Infect Dis Soc. 2019 Feb 22.
Effective diphtheria, tetanus toxoids, whole-cell pertussis (DTwP) vaccines became available in the 1930s, and they were put into routine use in the United States in the 1940s. Their use reduced the average rate of reported pertussis cases from 157 in 100 000 in the prevaccine era to <1 in 100 000 in the 1970s. Because of alleged reactions (encephalopathy and death), several countries discontinued (Sweden) or markedly decreased (United Kingdom, Germany, Japan) use of the vaccine. During the 20th century, Bordetella pertussis was studied extensively in animal model systems, and many “toxins” and protective antigens were described. A leader in B pertussis research was Margaret Pittman of the National Institutes of Health/US Food and Drug Administration. She published 2 articles suggesting that pertussis was a pertussis toxin (PT)-mediated disease. Dr Pittman’s views led to the idea that less-reactogenic acellular vaccines could be produced. The first diphtheria, tetanus, pertussis (DTaP) vaccines were developed in Japan and put into routine use there. Afterward, DTaP vaccines were developed in the Western world, and definitive efficacy trials were carried out in the 1990s. These vaccines were all less reactogenic than DTwP vaccines, and despite the fact that their efficacy was less than that of DTwP vaccines, they were approved in the United States and many other countries. DTaP vaccines replaced DTwP vaccines in the United States in 1997. In the last 13 years, major pertussis epidemics have occurred in the United States, and numerous studies have shown the deficiencies of DTaP vaccines, including the small number of antigens that the vaccines contain and the type of cellular immune response that they elicit. The type of cellular response a predominantly, T2 response results in less efficacy and shorter duration of protection. Because of the small number of antigens (3-5 in DTaP vaccines vs >3000 in DTwP vaccines), linked-epitope suppression occurs. Because of linked-epitope suppression, all children who were primed by DTaP vaccines will be more susceptible to pertussis throughout their lifetimes, and there is no easy way to decrease this increased lifetime susceptibility.
56) Measles outbreak and federal vaccine mandates
Jane M. Orient, M.D., Executive Director Association of American Physicians and Surgeons February 26, 2019
57) Measles: The New Red Scare By Roman Bystrianyk | Jul 31, 2015 | Essays, Science, US | 20 |
59) Biochemical Engineer Drops Bombshell Facts About Measles & The MMR Vaccine In Washington. March 10, 2019 By Arjun Walia CE
60) Woudenberg, Tom, et al. “Large measles epidemic in the Netherlands, May 2013 to March 2014: changing epidemiology.” Eurosurveillance 22.3 (2017).
“The incidence in infants aged less than 6 months was higher in 2013–2014 than in the 1999–2000 epidemic. This is likely to be related to the lower level of maternal antibodies in children born to vaccinated mothers compared with children born to unvaccinated mothers .”
61) The Impact of Vaccines on Mortality Decline Since 1900—According to Published Science By JB Handley, Children’s Health Defense Director and Co-Founder of Generation Rescue March 12, 2019
62) Roy, Felicia, et al. “Rapid identification of measles virus vaccine genotype by real-time PCR.” Journal of clinical microbiology 55.3 (2017): 735-743. Rapid identification of measles virus vaccine genotype by real-time PCR Roy Felicia J clin micro 2017
63) Zipprich J, Winter K, Hacker J, Xia D, Watt J, Harriman K, Centers for Disease Control and Prevention (CDC). 2015. Measles outbreak–California, Decem-ber 2014-February 2015. MMWR Morb Mortal Wkly Rep 64:153–154
64) March 15, 2019 Don’t Blame the Critics, FIX THE PROBLEM Childrens Health Defense Editorial by Alison Fujito
65) What is Driving Preventable Disease Outbreaks?
jameslyonsweiler in Cures February 21, 2019 770 Words
Given that two- and multi-dose MMR vaccination has not prevented measles circulation in the US, the strategy of blaming so-called anti-vaxxers (i.e., the Vaccine Risk Aware) will not stop transmission when exogenous infections come to the US. Adding 2% coverage will not prevent silent infection and silent transmission.
So what is driving Preventable Disease Outbreaks? Nothing, because they are not preventable with current vaccination technology.
Most transmissions in highly vaccinated populations are from the vaccinated, asymptomatic carriers with subclinical infections.
67) Rosen, Jennifer B., et al. “Outbreak of measles among persons with prior evidence of immunity, New York City, 2011.” Clinical infectious diseases 58.9 (2014): 1205-1210.
A measles outbreak occurred in New York City. All cases had prior evidence of measles immunity. Symptoms were consistent with measles. Laboratory results indicated secondary immune responses. This report documents measles transmission from an individual with verified secondary vaccine failure.
Background. Measles was eliminated in the United States through high vaccination coverage and a public health system able to rapidly respond to measles. Measles may occur among vaccinated individuals, but secondary transmission from such individuals has not been documented.
Methods. Suspected patients and contacts exposed during a measles outbreak in New York City in 2011 were investigated. Medical histories and immunization records were obtained. Cases were confirmed by detection of measles-specific immunoglobulin M and/or RNA. Tests for measles immunoglobulin G (IgG), IgG avidity, measurement of measles neutralizing antibody titers, and genotyping were performed to characterize the cases.
Results. The index patient had 2 doses of measles-containing vaccine; of 88 contacts, 4 secondary patients were confirmed who had either 2 doses of measles-containing vaccine or a past positive measles IgG antibody. All patients had laboratory confirmation of measles infection, clinical symptoms consistent with measles, and high-avidity IgG antibody characteristic of a secondary immune response. Neutralizing antibody titers of secondary patients reached >80 000 mIU/mL 3–4 days after rash onset and that of the index was <500 mIU/mL 9 days after rash onset. No additional cases of measles occurred among 231 contacts of secondary patients.
Conclusions. This is the first report of measles transmission from a twice-vaccinated individual with documented secondary vaccine failure. The clinical presentation and laboratory data of the index patient were typical of measles in a naive individual. Secondary patients had robust anamnestic antibody responses. No tertiary cases occurred despite numerous contacts. This outbreak underscores the need for thorough epidemiologic and laboratory investigation of suspected cases of measles regardless of vaccination status\
68) Failure to reach the goal of measles elimination. Apparent paradox of measles infections in immunized persons.Poland GA1, Jacobson RM.
69) The Re-Emergence of Measles in Developed Countries: Time to Develop the Next-Generation Measles Vaccines?
70) Judge in New York denies request to allow 44 unvaccinated students back in class. Gabriel Rom, Rockland/Westchester Journal News Published 7:46 p.m. ET March 12, 2019 | Updated 10:19 p.m. ET March 12, 2019 USA Today
WHITE PLAINS, N.Y. – A federal judge in New York on Tuesday denied a request for a temporary injunction that would have allowed 44 unvaccinated children to go back to class, citing an “unprecedented measles outbreak.”
“The plaintiffs have not demonstrated that public interest weighs in favor of granting an injunction,” U.S. District Court Judge Vincent Briccetti said in federal court in White Plains.
71) Parents Wanted Their Unvaccinated Children in School, but a Judge Said No. By Michael Gold March 13, 2019 New York Times
All of the children at the center of the lawsuit had received approved religion-based exemptions to vaccination, according to Michael Sussman, a lawyer for the parents who sued Rockland’s health department. But neither they nor their parents are Orthodox Jews, he said.
Rockland County’s so-called “exclusion orders” in December was the first time county officials had taken the step to ban unvaccinated children from schools, a county spokesman said. Under the orders, unvaccinated children were not allowed to attend targeted schools until the school’s vaccination rate reached 95 percent.
Even when schools did not have confirmed cases of measles, as with Green Meadow, officials were still worried that unvaccinated children could be exposed to measles in other public places, like shopping malls, and would then spread the disease at their schools, said Ed Day, the Rockland County executive.
At one point, 60 schools, many of them in ultra-Orthodox communities, and 6,000 students were affected by the orders, officials said.
The Rockland County Health Department said that as of last week, the immunization rate at Green Meadow’s elementary school was about 56 percent. Ms. Larson said that the school had paperwork to prove its rate at the elementary school was actually at 83 percent — still short of the threshold the county requires.
Green Meadow’s high school reached a 95 percent rate earlier this year and was cleared from excluding unvaccinated children in late January.
(72) Vardas, Eftyhia, and Stephanie Kreis. “Isolation of measles virus from a naturally-immune, asymptomatically re-infected individual.” Journal of clinical virology 13.3 (1999): 173-179.
The changing epidemiology of measles with mild measles cases increasingly being recognised in previously-vaccinated individuals, suggests that more asymptomatic or subclinical cases might be occurring. Although this has been clearly documented in previously-vaccinated individuals, the frequency of these asymptomatic infections in individuals previously naturally-infected with measles is not known. Also, it is not known whether these asymptomatic or mildly-infected individuals who do not display the full range of clinical signs of measles are capable of transmitting the virus to other susceptible persons.
OBJECTIVES:To demonstrate the isolation of measles virus (MV) from previously, naturally-immune individuals asymptomatically infected with measles while in close contact with acutely infected family members and to document the secondary immune responses (SIR) associated with asymptomatic measles infection.
STUDY DESIGN:Throat swab and urine specimens from five acute measles cases and their family contacts, taken within 5 days of onset of rash in each acute case, were used to isolate MV by tissue culture. Positive tissue culture results were confirmed by indirect immunofluorescence (IF) staining. Measles specific antibodies (IgG and IgM), IgG urea avidity and measles-neutralising antibodies were measured in the one family (index family) where an asymptomatic measles infection of a contact was demonstrated.
RESULTS:The acutely infected patient in the index family (T1/96) had a measles-neutralising antibody titre of < 1:10, measles IgG urea avidity of 24% and MV was isolated and confirmed by IF from urine and throat swab specimens. T1/96 represents acute measles infection after primary vaccine failure because he had a clear history of being vaccinated against measles as a child. MV was also successfully isolated from throat swab and urine specimens from the other four acute cases and from the urine but not the throat swab of an asymptomatically infected family contact in the index family (mother, T2/96). T2/96 had a history of natural measles infection as a child approximately 50 years ago. In addition to detectable MV in urine this contact also had a SIR with a rise in measles specific neutralising antibody titre. No virus was isolated from the other contact in the index family (father, T3/96) or from the contacts of the other four acute cases examined.
CONCLUSIONS:This is the first report of a confirmed asymptomatic MV infection, by MV isolation and IF testing and a concurrent SIR, in a previously naturally-immune contact of an acute case. The importance of these findings to the epidemiology and control of MV as well as the diagnostic value of MV urine isolation and IF confirmation for mild or asymptomatic cases must be examined further.
74) Sonoda, Satomi, Mitsuo Kitahara, and Tetsuo Nakayama. “Detection of measles virus genome in bone-marrow aspirates from adults.” Journal of general virology 83.10 (2002): 2485-2488. Detection of measles virus genome in bone-marrow aspirates from adults Sonoda Satomi J general virology 2002
We investigated the presence of the measles virus genome in order to identify asymptomatic infections in the adult population. Bone-marrow aspirates were obtained from 179 patients, 20-96 years of age, for the diagnosis of malignant diseases (29 with malignant lymphoma, 28 with acute leukaemia, 21 with myelodysplastic syndrome, five with multiple myeloma and 96 with other diseases). The measles virus genome was detected in 17 (9.5%) of 179 individuals by RT-PCR and 28 (15.6%) through hybridization. The genomes detected in bone marrow were all in the same cluster, D5, the strain circulating during the study period, and no evidence of persistent infection was obtained. We conclude that asymptomatic infections of measles virus are common in adults and the presence of the measles virus genome would not be related to the pathogenesis of illness.
75) Sonoda, Satomi, and Tetsuo Nakayama. “Detection of measles virus genome in lymphocytes from asymptomatic healthy children.” Journal of medical virology 65.2 (2001): 381-387.
A total of 342 samples of peripheral blood mononuclear cells (PBMC) were obtained from 145 healthy individuals, which we examined for the presence of measles virus genome RNA by reverse transcription-polymerase chain reaction (RT-PCR), to identify whether asymptomatic infection of measles virus has occurred in healthy children. Measles virus genome was detected in 11 (23.4%) of 47 nonimmunized individuals; all positives for RT-PCR were infants who experienced measles exposure. No genome was detected in those without measles exposure. In 83 individuals immunized with measles vaccine, the vaccine strain genome was detected in 10 (71.4%) of 14 recipients whose PBMC were obtained within 2 months of vaccination. Measles wild-type genome was detected in 36 (46.2%) of 78 individuals, 40 (25.2%) of 159 samples, who had been immunized more than 2 months before. The wild-type measles genome was also detected in 6 (46.2%) of 13 individuals who had been infected with measles in the distant past. The measles PCR-positive rate was not related to the period since immunization or natural infection. Sequence analysis of PCR products demonstrated they were all in the same cluster of D5 lineage, which was the circulating strain during the study period. We obtained 13 samples of nasopharyngeal secretion (NPS) simultaneously from individuals whose PBMC were positive for measles PCR but did not detect virus genome. Measles genome was, however, detected from NPS in cases of acute infection. We conclude that asymptomatic measles infection is common but would rarely become a source of transmission because of negative PCR in NPS.
76) Ma, Chao, et al. “Measles transmission among adults with spread to children during an outbreak: implications for measles elimination in China, 2014.” Vaccine 34.51 (2016): 6539-6544.
Despite high population immunity among children and adolescents following three rounds of measles vaccine supplementary immunization activities, sustained measles virus transmission still occurred among adults in this community. In 1986, a 2-dose MV schedule was recommended – one dose at 8 months followed by a second at 7 years of age. The recommended age for the second dose was lowered to 18 months in 2005 .
However, we have seen measles outbreaks among adults without children acting as measles virus reservoirs in recent years in China, raising our concern that susceptible adults could alone sustain measles virus transmission in community settings. We report a typical measles outbreak among adults in China that occurred in 2014, describing a pattern of measles virus transmission from adult to adult and then to children, in Kulun (KL) County.
77) Federal Judge Bans Healthy Children from School for Being Unvaccinated
Written by: Matt Agorist Published on: March 15, 2019
78) NYC News, December 6, 2018 NYC Bans Unvaccinated Children from Many Schools in Brooklyn
79) Judge Upholds Policy Barring Unvaccinated Students During Illnesses 2014 New York Times
In a case weighing the government’s ability to require vaccination against the individual right to refuse it, a federal judge has upheld a New York City policy that bars unimmunized children from public school when another student has a vaccine-preventable disease.(chickenpox)
80) Katayama, Yuko, et al. “Detection of measles virus mRNA from autopsied human tissues.” Journal of clinical microbiology 36.1 (1998): 299-301.By reverse transcription-PCR, measles virus (MV) mRNA was detected in the brain, kidney, spleen, liver, and lung tissues obtained from 23 (45.1%) of 51 autopsy subjects, with the detection rates of each tissue ranging from 8 to 20%. Sequence analysis revealed frequent mutations in the corresponding viral protein. These results suggest that MV mutants commonly persist in apparently healthy individuals.
81) Huiss, S., et al. “Characteristics of asymptomatic secondary immune responses to measles virus in late convalescent donors.” Clinical & Experimental Immunology 109.3 (1997): 416-420. Characteristics of asymptomatic secondary immune responses to measles virus Huiss Clin Exp Immun 1997
However, there is also evidence that measles virus (MV) can circulate in seropositive populations [4,5]. The characteristics of this transmission are so far only poorly understood. It is reasonable to assume that people susceptible to develop a secondary immune response (SIR) after re-exposure to measles are the most likely seropositive candidates to support viral transmission. There is no direct evidence that such a transmission could lead to clinical measles in seronegatives, although isolated cases without apparent contacts may be suggestive of such a mechanism.
Several observations indicate that measles virus can circulate among seropositive persons [4,5].
In a secluded population of seropositive vaccinees, most experienced an increase in measles titre several years after vaccination. In the absence of clinically overt measles, this suggested that the virus circulated also in healthy vaccinated individuals who could potentially transmit disease to seronegative people . It is likely that this requires a transient viraemia. People undergoing a clinically inapparent SIR are the most likely candidates to support such a transmission ofvirus. In this context, the transient nature of the SIR seems to indicate that such individuals can be efficiently protected from disease, but not from infection.
82) Pedersen, I. R., et al. “Subclinical measles infection in vaccinated seropositive individuals in arctic Greenland.” Vaccine 7.4 (1989): 345-348. Measles vaccination was performed in the arctic district of Scoresbysund, Greenland in 1968, which had never been exposed to natural measles. More than 90% of the total population was vaccinated and a 94-100% seroconversion was obtained. During a serological survey to examine the immunity status of the vaccinees, it was discovered that a temporary increase in measles antibodies took place in the majority of the population 2-4 years after the vaccination. This was not accompanied by clinically observed measles. Most likely, it was due to an inapparent measles infection in a population considered highly immune after vaccination.
83) de Vries, Willemien, Frans B. Plötz, and J. Wendelien Dorigo-Zetsma. “Measles infection despite 2-dose vaccination in health care workers.” The Pediatric infectious disease journal 33.9 (2014): 992. Measles infection despite 2-dose vaccination in health care workers de Vries Ped infect dis 2014
(84) Rota, Jennifer S., et al. “Two case studies of modified measles in vaccinated physicians exposed to primary measles cases: high risk of infection but low risk of transmission.” The Journal of infectious diseases 204.suppl_1 (2011): S559-S563.
In 2009, measles outbreaks in Pennsylvania and Virginia resulted in the exposure and apparent infection of 2 physicians, both of whom had a documented history of vaccination with >2 doses of measles-mumps-rubella vaccine. These physicians were suspected of having been infected with measles after treating patients who subsequently received a diagnosis of measles. The clinical presentation was nonclassical in regard to progression, duration, and severity. It is hypothesized that the 2 physicians mounted vigorous secondary immune responses typified by high avidity measles immunoglobulin G antibody and remarkably high neutralizing titers in response to intense and prolonged exposure to a primary measles case patient. Both of the physicians continued to see patients, because neither considered that they could have measles. Despite surveillance for cases among contacts, including unvaccinated persons, no additional cases were identified.
85) Sowers, Sun B., et al. “High concentrations of measles neutralizing antibodies and high-avidity measles IgG accurately identify measles reinfection cases.” Clin. Vaccine Immunol. 23.8 (2016): 707-716. High concentrations of measles neutralizing antibodies and high-avidity measles IgG accurately identify measles reinfection cases Sowers Sun Clin. Vaccine Imm 2016
86) Levy, Thomas E. Curing the Incurable: Vitamin C, Infectious Diseases, and Toxins. Xlibris Corporation, 2002.
87) Bring Back Childhood Measles Parties | Dr. Donald W. Miller, Jr. Bring Back Childhood Measles Parties | Dr. Donald W. Miller, Jr.
For 40 years, from 1974-2014, I taught and performed cardiac surgery at Seattle’s Swedish Medical Center, the Seattle VA Medical Center, and the University of Washington Medical Center. Now retired, as an Emeritus Professor of Surgery and former Chief, Division of Cardiothoracic Surgery at the University of Washington School of Medicine, I have written three books: The Practice of Coronary Artery Bypass Surgery, Atlas of Cardiac Surgery, and Heart in Hand, which is available free.
88) Measles vs. MMR Vaccine: Risks and Benefits By Donald W. Miller, Jr., MD February 12, 2015
89) Vaccine Safety Manual for Concerned Families and Health Practitioners [VACCINE SAFETY MANUAL FOR C-2E] [Paperback] Paperback – December 31, 2011
by NeilZ.Miller (Author)
90) Miller’s Review of Critical Vaccine Studies: 400 Important Scientific Papers Summarized for Parents and Researchers 1st Edition by Neil Z. Miller (Author)
91) VACCINES: AN ATTORNEY’S VIEWPOINT
Vaccines Must be Safe, Effective, Necessary, Legal, and Not “Leaky”
James Robert Deal, Attorney Revised February 12, 2017
92) Dr. Meryl Nass opposes LD798 and supports LD987. 3/13/19 testimony on vaccine exemptions to the Maine joint Education and Cultural Affairs Committee
93) Liang, Jennifer L., et al. “Prevention of pertussis, tetanus, and diphtheria with vaccines in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP).” MMWR Recommendations and Reports 67.2 (2018): 1.
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