Vitamin D Prevents Flu

Woman_sneezing-Vitamin_D_FluVitamin D Prevents Flu  by Jeffrey Dach MD

Are you sneezing, with a runny nose, and aches and pains? You may have the common cold.  Rather than go through a week of misery, better to prevent Colds with Vitamin D.

A study published Feb 23 in the Archives of Internal Medicine showed that Vitamin D prevents the common cold.  In this study, patients with low vitamin D levels had 40% more flu episodes.(1)  Others have confirmed these findings. According to  a study by Dr Mitsuyoshi, who writes in 2010:

This study suggests that vitamin D3 supplementation during the winter may reduce the incidence of influenza A, especially in specific subgroups of schoolchildren.(7)

Dr Camargo reported in in Pediatrics 2012, a randomized trial of vitamin D supplementation and risk of acute respiratory tract infection in Mongolia .  Risk of acute URI was reduced in half by Vitamin D supplementation. :

“a randomized controlled trial of 247 Mongolian children with vitamin D deficiency in winter, with double-blinding and 99% follow-up, vitamin D supplementation significantly halved the risk of acute respiratory infections”(12)

In a 2006 reprt, Dr Cannell writes about seasonality of influenza epidemics which tend to occur in winter when vitamin D from sun exposure is lowest.(12) He says:

vitamin D deficiency is common in the winter, and activated vitamin D, 1,25(OH)2D, a steroid hormone, has profound effects on human immunity. 1,25(OH)2D acts as an immune system modulator, preventing excessive expression of inflammatory cytokines and increasing the ‘oxidative burst’ potential of macrophages. Perhaps most importantly, it dramatically stimulates the expression of potent anti-microbial peptides, which exist in neutrophils, monocytes, natural killer cells, and in epithelial cells lining the respiratory tract where they play a major role in protecting the lung from infection. Volunteers inoculated with live attenuated influenza virus are more likely to develop fever and serological evidence of an immune response in the winter. Vitamin D deficiency predisposes children to respiratory infections. Ultraviolet radiation (either from artificial sources or from sunlight) reduces the incidence of viral respiratory infections, as does cod liver oil (which contains vitamin D). An interventional study showed that vitamin D reduces the incidence of respiratory infections in children. “.(9)

These findings suggest Vitamin D helps the immune system fight off viral illness like the flu.  Vitamin D is actually a hormone which attaches directly to cellular DNA and is involved in prevention of autoimmune diseases.  Low vitamin D levels have been linked to chronic diseases such as auto-immune disease, multiple sclerosis, heart disease, and increased rate of cancer.(13)  In fact, low vitamin D levels have been associated with increased over-all mortality.(14)  We routinely check vitamin D3 levels every six months, and provide supplements when low. Don’t forget to combine your Vitamin D with Vitamin K (MK-7).

Vitamin K is there Anything it Cant Do?

Jeffrey Dach MD
7450 Griffin Road Suite 190
Davie, Fl 33314
954 792-4663

Buy Vitamin D3 with MK7-K2 .

Articles with Related Interest:

Colostrum 3 times more effective than Flu Vaccine

Flu Shot only 10 % Effective

Stop Vitamin D, Are You Joking>

Vitamin D Deficiency, the Ignored Epidemic

The Failure of Global Polio Eradication

References and Links

1) Association Between Serum 25-Hydroxyvitamin D Level and Upper Respiratory Tract Infection in the Third National Health and Nutrition Examination Survey. Adit A. Ginde, MD, MPH; Jonathan M. Mansbach, MD; Carlos A. Camargo Jr, MD, DrPH Arch Intern Med. 2009;169(4):384-390.

2)  Adit A. Ginde; Jonathan M. Mansbach; Carlos A. Camargo Jr.
Association Between Serum 25-Hydroxyvitamin D Level and Upper Respiratory Tract Infection in the Third National Health and Nutrition Examination Survey. Archives of Internal Medicine, 2009; 169 (4): 384

3)  Vitamin D Deficiency May Increase Risk Of Colds, Flu
ScienceDaily (Feb. 24, 2009) — Vitamin D may be an important way to arm the immune system against disorders like the common cold, report investigators from the University of Colorado Denver (UC Denver) School of Medicine, Massachusetts General Hospital (MGH) and Children’s Hospital Boston.

4)  Vitamin D may protect against common cold.
Deficiency of vitamin D is common, particularly in winter.
People with low blood levels of vitamin D more likely to report a recent cold By Theresa Tamkins,Vitamin D may protect people — especially those with asthma and other chronic lung conditions — from colds and other respiratory tract infections, according to the largest study to date to look at the link.People with low blood levels of vitamin D were more likely to have had a recent cold.

5)  Too Little Vitamin D May Mean More Colds and Flu
By Alan Mozes, HealthDay Reporter MONDAY, Feb. 23 (HealthDay News) –Forget the apple. The largest study of its kind to date shows that vitamin D each and every day is what will keep the doctor away when it comes to the common cold or the flu.

6) Stop Vitamin D ? Surely You Must be Joking.

7) Urashima, Mitsuyoshi, et al. “Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren–.” The American journal of clinical nutrition 91.5 (2010): 1255-1260. Vitamin D supplementation to prevent influenza A in schoolchildren Urashima Mitsuyoshi Am j clin nut 2010

Background: To our knowledge, no rigorously designed clinical trials have evaluated the relation between vitamin D and physician-diagnosed seasonal influenza.
Objective: We investigated the effect of vitamin D supplements on the incidence of seasonal influenza A in schoolchildren.
Design: From December 2008 through March 2009, we conducted a randomized, double-blind, placebo-controlled trial comparing vitamin D3 supplements (1200 IU/d) with placebo in schoolchildren. The primary outcome was the incidence of influenza A, diagnosed with influenza antigen testing with a nasopharyngeal swab specimen.
Results: Influenza A occurred in 18 of 167 (10.8%) children in the vitamin D3 group compared with 31 of 167 (18.6%) children in the placebo group [relative risk (RR), 0.58; 95% CI: 0.34, 0.99; P = 0.04]. The reduction in influenza A was more prominent in children who had not been taking other vitamin D supplements (RR: 0.36; 95% CI: 0.17, 0.79; P = 0.006) and who started nursery school after age 3 y (RR: 0.36; 95% CI: 0.17, 0.78; P = 0.005). In children with a previous diagnosis of asthma, asthma attacks as a secondary outcome occurred in 2 children receiving vitamin D3 compared with 12 children receiving placebo (RR: 0.17; 95% CI: 0.04, 0.73; P = 0.006).
Conclusion: This study suggests that vitamin D3 supplementation during the winter may reduce the incidence of influenza A, especially in specific subgroups of schoolchildren. This trial was registered at https://center.umin.ac.jp as UMIN000001373.

8)  Nurses and Healthcare Workers Across the U.S. Are Refusing Mandatory Flu Vaccines by Claire Dwoskin, Founder, Childrens Medical Safety Research Institute

9) Cannell, J. J., et al. “Epidemic influenza and vitamin D.” Epidemiology & Infection 134.6 (2006): 1129-1140.

In 1981, R. Edgar Hope-Simpson proposed that a ‘seasonal stimulus’ intimately associated with solar radiation explained the remarkable seasonality of epidemic influenza. Solar radiation triggers robust seasonal vitamin D production in the skin; vitamin D deficiency is common in the winter, and activated vitamin D, 1,25(OH)2D, a steroid hormone, has profound effects on human immunity. 1,25(OH)2D acts as an immune system modulator, preventing excessive expression of inflammatory cytokines and increasing the ‘oxidative burst’ potential of macrophages. Perhaps most importantly, it dramatically stimulates the expression of potent anti-microbial peptides, which exist in neutrophils, monocytes, natural killer cells, and in epithelial cells lining the respiratory tract where they play a major role in protecting the lung from infection. Volunteers inoculated with live attenuated influenza virus are more likely to develop fever and serological evidence of an immune response in the winter. Vitamin D deficiency predisposes children to respiratory infections. Ultraviolet radiation (either from artificial sources or from sunlight) reduces the incidence of viral respiratory infections, as does cod liver oil (which contains vitamin D). An interventional study showed that vitamin D reduces the incidence of respiratory infections in children. We conclude that vitamin D, or lack of it, may be Hope-Simpson’s ‘seasonal stimulus’.

10) Ginde, Adit A., Jonathan M. Mansbach, and Carlos A. Camargo. “Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey.” Archives of internal medicine 169.4 (2009): 384-390.

11) Sabetta, James R., et al. “Serum 25-hydroxyvitamin d and the incidence of acute viral respiratory tract infections in healthy adults.” PloS one 5.6 (2010): e11088

12) Camargo, Carlos A., et al. “Randomized trial of vitamin D supplementation and risk of acute respiratory tract infection in Mongolia.” Pediatrics (2012): peds-2011.
a randomized controlled trial of 247 Mongolian children with vitamin D deficiency in winter, with double-blinding and 99% follow-up, vitamin D supplementation significantly halved the risk of acute respiratory infections

13) Holick, Michael F., and Tai C. Chen. “Vitamin D deficiency: a worldwide problem with health consequences–.” The American journal of clinical nutrition 87.4 (2008): 1080S-1086S. Vitamin D deficiency worldwide problem with health consequences Holick Michael Am J Clin Nutr 2008

14) Gaksch, Martin, et al. “Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium.” PLoS One 12.2 (2017): e0170791.

15)  Rondanelli, Mariangela, et al. “Self-care for common colds: the pivotal role of vitamin D, vitamin C, zinc, and Echinacea in three main immune interactive clusters (physical barriers, innate and adaptive immunity) involved during an episode of common colds—Practical advice on dosages and on the time to take these nutrients/botanicals in order to prevent or treat common colds.” Evidence-Based Complementary and Alternative Medicine 2018 (2018).

Above image are courtesy of wikimedia commons and are in the public domain.

Jeffrey Dach MD
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Vitamin D Prevents Flu
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Vitamin D Prevents Flu
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Are you sneezing, with a runny nose, and aches and pains? You may have the common cold.  Rather than go through a week of misery, better to prevent Colds with Vitamin D.
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Jeffrey Dach MD
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