COX2 Inhibitors As Anti-Cancer Agents The COX2 (Cyclo-Oxygenase) pathway is upregulated in cancer, and COX2 inhibitors (celecoxib) can inhibit cell proliferation, tumor  invasiveness, and angiogenesis.  They can also overcome apoptosis resistance by BCL2, and overcome P-glycoprotein/MDR drug resistance, as well … Continue reading →