Amazon Reviews for Bioidentical Hormones 101 – 2nd Edition: Menopausal Hormone Replacement by Jeffrey Dach MD

Thanks to the nine reviewers who all gave my book 5 star ratings! However, we need more Amazon book reviews. If you have ordered the ebook, audible or paperback versions, we need your review right away! Hopefully a favorable one. For your reading enjoyment, I have reposted here are a few of the current book reviews:

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Dr. Anat 5.0 out of 5 stars
If you read one book on hormone replacement, let it be this.
Reviewed in the United States on May 28, 2025
Format: Audiobook Verified Purchase

As a menopause specialist and board-certified OB/GYN with experience in bioidentical hormone replacement therapy, I consider Dr. Jeffrey Dach’s Bioidentical Hormones 101 one of the most important texts in our field. This 592-page comprehensive guide translates over 20 years of clinical experience into an evidence-based resource that every practitioner treating women in midlife should study closely.

In a medical climate still dominated by misinformation, Dr. Dach’s work cuts through decades of confusion with scientific precision. He dismantles the flawed assumptions that have shaped hormone replacement therapy for over two decades, backing every statement with meticulous references from peer-reviewed literature.

The 2025 second edition is fully updated and revised, incorporating the latest research while preserving the core principles that make bioidentical hormones both safe and effective when prescribed correctly.

One of the book’s key strengths lies in its detailed explanation of the biological distinctions between estradiol (E2) and estriol (E3). While conventional medicine often treats all estrogens as equivalent, research shows otherwise. Estriol (E3) is breast cancer protective, counteracting estradiol’s proliferative effects in breast tissue. Studies cited demonstrate that women who develop breast cancer often have lower E3 levels than those who remain cancer-free. Dr. Dach expands on Dr. H.M. Lemon’s “estrogen quotient” (EQ), showing that higher E3 ratios correlate with lower breast cancer risk.

This distinction underpins the rationale for BiEst formulations (E2 + E3 in specific ratios), which represent a more physiologic and protective approach than estradiol monotherapy.

Equally compelling is Dr. Dach’s analysis of testosterone’s role in breast cancer protection, a topic widely misunderstood in conventional medicine. He presents strong evidence that testosterone and its metabolites exert anti-proliferative effects via the androgen receptor, reducing breast cancer risk by up to 39 percent in some studies. The metabolite 3β-diol’s ability to activate the tumor-suppressor estrogen receptor beta (ERβ) provides additional protection.

The discussion of hormone receptors, ERα versus ERβ, is one of the book’s most critical contributions. ERα promotes cell proliferation, whereas ERβ acts as a tumor suppressor. Understanding which hormones and metabolites target these receptors is fundamental to designing safe, effective, individualized therapy.

Dr. Dach also exposes the dangerous conflation of natural progesterone with synthetic progestins. He shows that synthetic progestins such as medroxyprogesterone acetate (MPA) used in the Women’s Health Initiative (WHI) increase breast cancer risk, while natural progesterone demonstrates neutral or protective effects. A meta-analysis cited reveals a 33 percent lower breast cancer risk in women using estrogen with micronized progesterone compared to synthetic progestins.

This distinction is not academic; it is lifesaving.

What makes Bioidentical Hormones 101 exceptional is its scientific rigor. Each concept is supported by extensive citations, presented in a clear and logical format that allows practitioners to follow the evidence step by step. Complex endocrine concepts are translated into practical clinical guidance without sacrificing accuracy.

This book is indispensable for practitioners who want to:

Understand the biochemical differences between bioidentical and synthetic hormones

Recognize the importance of receptor specificity

Appreciate why formulation, timing, and delivery route matter

Interpret conflicting research critically

Develop evidence-based, patient-centered protocols

Dr. Dach provides the foundation for moving beyond fear-based medicine toward true evidence-based care in menopause management.

While dense for casual readers, the book empowers patients willing to engage deeply with the science, clarifying why bioidentical hormones differ fundamentally from synthetic ones and why personalization is key.

The updated 2025 edition reinforces that the foundational hormonal science remains sound. Subsequent research has only strengthened Dr. Dach’s conclusions.

Bioidentical Hormones 101 belongs on every hormone practitioner’s desk. It bridges academic research and clinical practice with precision, clarity, and integrity. In a field still clouded by misinformation and pharmaceutical bias, this work stands as a beacon of truth and clinical excellence.

As a board-certified OB/GYN and menopause expert, this is my professional opinion based on years of clinical experience treating women through perimenopause and menopause. Dr. Dach’s work continues to shape evidence-based care and remains an indispensable resource for those dedicated to optimal patient outcomes.

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Carol Petersen 5.0 out of 5 stars
A Clear Guide Through the Hormone Therapy Maze
Reviewed in the United States on June 3, 2025
Format: KindleVerified Purchase

A Clear Guide Through the Hormone Therapy Maze

Bioidentical Hormones 101 by Dr. Jeff Dach is a much-needed resource for anyone confused or concerned about hormone therapy. In today’s healthcare landscape, patients and even many professionals are bombarded with conflicting information from medical societies, pharmaceutical companies, and the media. Dr. Dach cuts through this noise with kindness and clarity, offering a thorough, evidence-based look at bioidentical hormones.

What sets this book apart is its ability to untangle complex medical literature and present it in an approachable way. Dr. Dach explains how bioidentical hormones—those that exactly match what our bodies produce—can address hormone deficiencies safely and effectively. He also sheds light on the commercial interests behind synthetic alternatives, helping readers understand why so much confusion exists.

The book is especially valuable for women who have felt disempowered by poor healthcare choices or who are haunted by fears of breast cancer, other cancers, or blood clots. Dr. Dach reviews the evidence carefully, separating fact from fiction, and empowers readers to make informed decisions about their health.

Each chapter is organized to build confidence and understanding, making complex topics easy to grasp. By the end, readers will feel equipped to advocate for themselves and make sound choices about hormone therapy.

Bioidentical Hormones 101 is a lifeline for anyone navigating the often bewildering world of hormone replacement. Dr. Dach’s expertise and compassion shine through, making this book a gift to patients and professionals alike. I highly recommend it and look forward to future volumes from Dr. Dach.

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Amazon Customer 5.0 out of 5 stars
Comprehensive review of BioIdentical hormones
Reviewed in the United States on September 17, 2025
Format: Paperback Verified Purchase

This is a second edition and reads differently than the original Bioidentical 101. This text addresses even more content than the first edition, and continues to be FULL of research, with plenty of references for each chapter. This should be mandatory reading in medical school, or any healthcare related field. It is a great reference. This book has great information for the lay person as well as medical professionals.

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Donna D White 5.0 out of 5 stars
The most complete, research-backed guide to bioidentical hormones.
Reviewed in the United States on April 16, 2025
Format: Audiobook Verified Purchase

A Must-Have Resource for Every Hormone Provider and Patient

By Donna White, Founder of the BHRT Training Academy

Dr. Jeffrey Dach’s Bioidentical Hormones 101 Volumes One, Two, and Three represent the most comprehensive and evidence-based compilation on bioidentical hormone therapy I have ever encountered—and I’ve been in the field for over 30 years. These volumes are a tour de force, translating decades of critical medical literature into clear, accessible language that empowers both providers and patients.

This isn’t just a book series—it’s an encyclopedia of hormone health. Dr. Dach skillfully dismantles myths, clarifies the differences between synthetic and bioidentical hormones, and backs every point with rigorous research. Whether you’re a healthcare provider prescribing hormones or a woman trying to make informed decisions about your body, these books are indispensable.

If you’re tired of outdated narratives and are ready for science-based truth about hormone therapy, this series is exactly what you need. I’ve already recommended it to the providers enrolled in my BHRT Training Academy—and now I recommend it to you.

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Family Shopper 5.0 out of 5 stars
Detailed information on hormone care safety and research data
Reviewed in the United States on September 17, 2025
Format: Paperback Verified Purchase

Astounding book with depth and breath of the knowledge we all need on hormone care. We are a society of individuals looking for the data in a consumable way for care, and data to support our safety and care. As a life long learner I am always looking at the data in a way that I can help my patients make good clinical decisions on hormone care. Please take the leap and get this book it will not disappoint!

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Amazon Customer 5.0 out of 5 stars
A Must-Read Book for All Women and All Medical Professionals who Treat Menopausal Women
Reviewed in the United States on July 16, 2025
Format: Audiobook

I’ve been following Dr. Dach’s work for years, having read his first book, kept up with his blogs, and watched his science-based lectures. He is one of the few voices in this space who consistently honors both the research and the patient experience. That balance is rare and so needed.

There is so much noise on social media about hormones. People speaking with authority who haven’t done their homework, spreading fear and confusion, and exacerbating the polarization surrounding hormones. The truth is: hormones are not controversial. They’re vital for life, and Dr. Dach’s book does an excellent job of explaining how hormones function in the body, why they’re essential for long-term health and vitality, and what happens when we live in a state of imbalance or deficiency.

This isn’t just theory or opinion. Bioidentical Hormones 101 is a science-based deep dive. It is clear, well-referenced, and focused on empowering you with a fundamental understanding. Dr. Dach unpacks decades of medical literature and lays it out in a way that feels both accessible and trustworthy. You don’t need a medical degree to follow it, but you will finish feeling like you can have an informed conversation with any provider.

Dr. Dach helps separate fear from fact, especially around big topics like breast cancer, blood clots, and other concerns that have historically been misunderstood or misrepresented in conventional care. Each chapter builds on the last, creating a roadmap that supports both patients and practitioners. Whether you’re exploring perimenopause, menopause, or simply trying to feel more like yourself again, or you’re a provider interested in learning more about menopause so that you can better serve your patients, this book is a game-changer.

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If you liked this article, you might like my book, Bioidentical Hormones 101, 2nd Edition (2025), paperback and ebook on Amazon. 

Click Here for link to Paperback Version of Bioidentical Hormones 101 second edition (2025). The paperback contains all three volume ebooks.

Free Video Introduction to Book:

Introduction Video to Bioidentical Hormones 101 Second Edition (2025)

Bioidentical Hormones for Breast Cancer Survivors  Video Presentation

Link to my Free e-Book Bioidentical Hormones 101

Articles with Related Interest:

Errors in Modern Medicine, the Fear of Estrogen

Hormone Replacement for Breast Cancer Survivors Part One

Hormone Replacement for Breast Cancer Survivors Part Two

Estrogen Metabolism, Iodine, 2MEO Part Three

Testosterone for Breast Cancer Prevention and Treatment

Introduction Video to Bioidentical Hormones 101 Second Edition (2025)

All Bioidentical Hormone Articles by Jeffrey Dach MD

The Safety of Transdermal Estrogen Part One

The Safety of Transdermal Estrogen vs. Oral Estrogen Part Two

Jeffrey Dach MD
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Published on January 29th, 2026 by Jeffrey Dach MD