Overdosing on Tylenol While Pregnant

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Overdosing on Tylenol While Pregnant by Jeffrey Dach MD

This was bound to happen sooner or later. Tylenol overdose will cause liver failure and death. Here is a video discussing a pregnant liberal who took too much Tylenol after hearing Donald Trump say it causes autism. In order to make a political statement, she took an overdose, and she is now in the ICU and is not expected to survive. Nicole Sirotek RN, @NicoleSirotek, the Executive Director of American Frontline Nurses got a “very frantic call at 4am from a husband whose wife is now dying of liver failure…

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News Conference Roosevelt Room, White House, Sept. 22, 2025

In a recent news conference two major announcements were made by HHS secretary RFKjr, FDA commissioner Marty Makary, Dr. Mehmet Oz, President Trump regarding autism spectrum disorder including leucovorin (activated folate) treatments and acetaminophen (Tylenol)  risks during pregnancy.

This can be found HERE posted on X by Children;s Health Defense. 

Firstly, a large number of studies show correlation between Tylenol exposure during pregnancy and fetal neurodeveloment disorder including ADHD and autism spectrum disorder. The latest is a large meta-analysis of 46 studies by Dr. Andrea A Baccarelli Dean of Harvard School of Public Health.

There is also a 2019 study by Dr. Yuelong Ji looking at acetaminophen levels in cord blood sampled at birth and later finding of ADHD and autism. The highest third of acetaminophen level in cord blood was associated with a 3 times greater risk for autism.

Dr. Yuelong Ji comes from Peking, China and did a postdoctoral fellow at the Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland. He authored the study: Ji, Yuelong, et al. “Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood.” JAMA Psychiatry 77.2 (2019): 180.

Folate Receptor Antibodies

Secondly, there are folate receptor antibodies in autistic children which mimic a folate deficiency state. Activated folate in the form of methyl folate or Leukovorin was suggested by Dr. Makary. Studies show improvement in speech in autistic kids treated with activated folate (methyl folate).

I sent out two newsletters discussing both of these issues 13 years ago.;

Tylenol Acetaminophen Liver Toxicity by Jeffrey Dach MD

Important Breakthrough Folate in Autism by Jeffrey Dach MD

Tylenol Overdose is Dangerous

Tylenol (acetaminophen) overdose is dangerous and is fairly easy to overdose on it. Tylenol is responsible for 30-50,000 hospitalizations per year and some will go on to liver failure requiring transplant in 2000 patients per year. The antidote is NAC (N-acetyl cysteine) which restores glutathione levels. Tylenol overdose creates the highly oxidative metabolite NAPQI, N-acetyl-p-benzoquinone imine. NAPQI is highly oxidative and quickly depletes glutathione, the major intracellular antioxidant. This will destroy mitochondria in the liver, causing liver failure in a pattern called centrilobular necrosis.

Left Image: Normal Liver Histology with pattern of sinusoids arranged as a spoke wheel around the central vein. Courtesy of: Basarslan, Fatmagul, et al. “Effects of ebselen on radiocontrast media–induced hepatotoxicity in rats.” Toxicology and Industrial Health 29.8 (2013): 746-752. Kemal Turker ULUTAŞ Doctor of Medicine

Left Image: Centrilobular necrosis from acetaminophen toxicity with loss of sinusoidal pattern as this is filled in with necrotic cells.
Courtesy of Wikimedia Commons. Ciobanu AO, Gherasim L (2018). “Ischemic Hepatitis – Intercorrelated Pathology.”. Maedica (Bucur) 13 (1): 5-11. PMID 29868133. PMC: 5972787. Author: Mikael Häggström, M.D. 27 July 2021.

Why We Dont Like Tylenol – Josh Redd

Dr. Joshua J. Redd is a naturopathic physician, chiropractor, and functional medicine practitioner specializing in Hashimoto’s thyroiditis and other low thyroid conditions. He is the founder and owner of RedRiver Health and Wellness Center. In this video, Dr. Redd explains how Tylenol depletes glutathione and is dangerous:

Maternal Immune Activation

Is it the Tylenol drug, or the underlying viral illness and fever which causes the maternal immune activation, and then triggers inflammatory cytokines to travel through the placenta to the fetus and cause neuro-inflammation and impaired neuro-development? Some would say it is the combination of Tylenol and maternal and/or fetal \/a<<ination that causes the immune activation and glutathione depletion which leads to fetal neurodevelopment disorder. I would agree with this the discussion by Christina Parks (below) on this..

Johnson and Johnson, makers of Tylenol have publicly advised to avoid their products during pregnancy.  See this quote from the National Pulse from the official Tylenol account (then under Johnson & Johnson):

“We actually don’t recommend using any of our products while pregnant.”

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The Elephant in the Room

During the news conference, President Trump brought up the Amish in Lancaster County Pensylvania. They do not \/a<<inate and they have no autism. RFK, Jr. said: “Some 40% to 70% of mothers who have children with autism believe that their child was injured by a vaccine. President Trump believes that we should be listening to these mothers instead of gaslighting and marginalizing them, like prior administrations.” One thing is clear. The elephant in the room is the immune activation from hyper\/a<<ination which is the obvious cause of ADHD, Autism and other neurodevelopmental disorders in children. This was discussed in previous newsletter HERE.

The below video is Dr. Christina Parks, PhD in Cellular and Molecular Biology from the University of Michigan Medical School discussing how Tylenol depletes glutathione, the major intracellular antioxidant. Glutathione is needed to quench inflammation associated with immune activation. If glutathione is depleted by Tylenol, any type of immune activation (such as a battery of \/a<<ines) leads to uncontrolled brain inflammation, encephalitis and neurodevelopmental disorders such as autism.

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Tylenol is a Marker for \/a<<ination

The pregnant mom will typically take the Tylenol for fever induced by four \/a<<ines during pregnancy. Two to eight years later, the child is diagnosed with autism after a battery of \/a<<ines. The confounding variable in all the Tylenol/Autism studies is the \/a<<ines. The use of Tylenol serves as a marker for \/a<<ination. Here is Nicolas Hulscher, MPH discussing these same points:

Conclusion: Overdosing on Tylenol causes liver failure and death and should not be used as a political statement during pregnancy. The various causes of immune activation in pregnancy and early childhood are additive in the etiology of neuroinflammation, neurodevelopment disorders, ADHD and autism. The elephant in the room is hyper\/a<<ination which is the number one cause of immune activation and neuro-inflammation in pregnancy and in children. Taking Tylenol for \/a<<ine induced fever will deplete glutathione and make immune activation/ neuroinflammation worse. When will RFKjr, Marty Makary and President Trump announce hyper\/a<<ination as the number one risk factor for autism? Soon, I hope.

Articles with Related Interest

Tylenol Acetaminophen Liver Toxicity

Important Breakthrough Folate in Autism

Hypervaccination and Neurodevelopmental Disorders, ADHD, Autism

Jeffrey Dach MD
7450 Griffin Road Suite 180/190
Davie, Florida 33314
954-792-4663

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References

Tylenol, Folate and Autism

Important Breakthrough Folate in Autism by Jeffrey Dach MD

Folate, also called Vitamin B9, is an essential nutrient needed for synthesis of brain neurotransmitters, Serotonin, Dopamine and Norepinephrine.

Folate deficiency is associated with depression, Attention Deficit Disorder (ADD), and other neuropsychiatric disorders.

Disturbed folate metabolism is also a risk factor for blood clots (thromboembolism) and increased risk of all cancers.
5MTHF is the Active Form of Folate

Folate itself cannot enter the brain. It must first attach to Folate Receptors (FR) in the choroid plexus and then be converted to the active form, MTHFR, which then may cross the blood brain barrier to enter the brain tissue.

The active form of folate is 5MTHF, (also called 5-Methyl-Tetra Hydro-Folate) This form of the vitamin can easily cross the blood brain barrier, enter the brain and promote neurotransmitter production.
Folate Receptor Antibodies

In Autism, the Folate Receptor is non-functioning because of auto-antibodies. This is a form of autoimmune disease in which an immune response is mounted against the Folate Receptor. This is a bad thing because the Folate Vitamin is not working and cannot get into the brain where it is needed.
75% of Autistic Children Have Folate Receptor Antibodies

Dr. Frye’s study found that Folate Receptor Antibodies were present in 75% of the 93 autistic children studied. In 16 children in which spinal fluid samples were studied, the presence of Folate Receptor Antibodies correlated with reduced cerebrospinal fluid 5-MTHF levels.
Treatment with Activated Folate

The autistic children were treated with up to 50 mg per day of Leucovorin over 4 months. This is an activated folate vitamin. One third of treated children were deemed “Moderate” to “Much Improved” in verbal communication, receptive and expressive language, attention and stereotypical behavior. The authors recommended empiric treatment of all autistic children with activated Folate supplements ( Such as 5mg caps 5MTHF from Thorne)

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Andrea Baccarelli acetaminophen autism

Andrea A Baccarelli 4
Harvard T.H. Chan School of Public Health, Harvard University, 677 Huntington Ave, Boston, MA

Prada, Diddier, et al. “Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology.” Environmental Health 24.1 (2025): 56.

We identified 46 studies for inclusion in our analysis. Of these, 27 studies reported positive associations (significant links to NDDs), 9 showed null associations (no significant link), and 4 indicated negative associations (protective effects).

Higher-quality studies were more likely to show positive associations. Overall, the majority of the studies reported positive associations of prenatal acetaminophen use with ADHD, ASD, or NDDs in offspring, with risk-of-bias and strength-of-evidence ratings informing the overall synthesis.

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BREAKING MAHA FAIL: Trump and RFK Jr. Mostly Blame Tylenol for AUTISM Acetaminophen exacerbates vaccine damage, but does NOT cause it. 2nd Smartest Guy in the World Sep 22, 2025

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Tylenol Acetaminophen Liver Toxicity by Jeffrey Dach MD
Posted on March 25 2016

Acetaminophen Toxicity Suneil Agrawal; Brian P. Murray; Babak Khazaeni.
StatPearls [Internet].Last Update: April 10, 2025.

Acetaminophen toxicity accounts for 50% of all reported cases of liver failure in the United States and 20% of all liver transplants.

Acetaminophen poisoning is responsible for 56,000 emergency department visits, 2600 hospitalizations, and 500 deaths annually in the United States, with 50% of these cases being unintentional overdoses.[5][6][7] Approximately 30,000 pediatric acetaminophen poisoning cases are reported to the National Poison Data System annually.

About 8% of acetaminophen is metabolized by hepatic cytochrome P450 subfamilies—CYP2E1, CYP1A2, and CYP3A4—through the mixed-function oxidase pathway, generating a toxic, highly reactive, electrophilic intermediate N-acetyl-p-benzoquinoneimine (NAPQI).

in cases of acetaminophen toxicity, an increased production of NAPQI occurs, depleting hepatic glutathione stores.

NAPQI gains an additional aryl group and binds covalently to cysteine groups on hepatic macromolecules, particularly mitochondrial proteins, forming NAPQI-protein adducts. The process initiates an irreversible cascade. The results of NAPQI-protein adduct formation include:

Oxidative hepatocyte injury
Alteration of the mitochondrial ATP-synthase alpha-subunit
Hepatocellular centrilobular necrosis

The 4-hour serum acetaminophen level should be plotted on the Revised Rumack-Matthew nomogram. If the patient’s serum acetaminophen level falls at or above the treatment line, N-acetylcysteine administration is necessary.

Is Acetaminophen Fanning the Flames of Vaccine Injury?
TOPICS: acetaminophenparacetamol Posted By: VaxxterAdmin 08/09/2019  By Dani Lasher, Vaxxter Contributor Tenpennyreport

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Prioritized List of 24 Alternatives (Best Efficacy First)

Curcumin (Turmeric Extract) Efficacy: High. Numerous studies show curcumin’s potent anti-inflammatory effects, comparable to some NSAIDs for arthritis and muscle pain. It also has mild fever-reducing properties.
Evidence: Meta-analyses support its use for osteoarthritis (reduces pain and stiffness) and systemic inflammation. Piperine-enhanced formulations improve absorption.

Use: 500–2,000 mg daily (standardized to 95% curcuminoids).
Notes: Broad applicability; best for chronic inflammation and pain.

Boswellia (Indian Frankincense) Efficacy: High. Standardized extracts (65% boswellic acids) reduce joint pain and inflammation, particularly for osteoarthritis and rheumatoid arthritis.
Evidence: Clinical trials show significant pain relief and improved joint function, often within weeks.
Use: 300–600 mg, 2–3 times daily.
Notes: Complements curcumin; strong for musculoskeletal issues.

New Chapter Zyflamend Efficacy: High. Combines curcumin, ginger, rosemary, and other anti-inflammatory herbs, with studies showing efficacy for joint pain and inflammation.
Evidence: Proprietary blend backed by small clinical trials for arthritis and muscle recovery.
Use: 2 capsules daily.
Notes: Synergistic formula enhances efficacy; widely studied.

Omega-3 Fatty Acids (Fish Oil/Algae Oil) Efficacy: High. EPA/DHA reduce systemic inflammation and joint pain, especially in rheumatoid arthritis.
Evidence: Meta-analyses confirm benefits for arthritis and muscle soreness; long-term use needed for full effect.
Use: 1,000–3,000 mg EPA/DHA daily.
Notes: Best for chronic inflammation; less immediate for fever.

White Willow Bark Efficacy: High. Salicin acts like aspirin, reducing pain and fever effectively.
Evidence: Studies support its use for lower back pain and fever; comparable to low-dose aspirin.
Use: 120–240 mg salicin daily.
Notes: Fast-acting for pain and fever but avoid in aspirin-sensitive individuals.

Capsaicin (Cayenne Pepper) Efficacy: High. Topical capsaicin significantly reduces neuropathic and musculoskeletal pain.
Evidence: Strong clinical evidence for arthritis and muscle pain; less data for fever.
Use: 0.025–0.1% cream, applied 3–4 times daily.
Notes: Immediate relief for localized pain; not systemic.

CBD Oil (Cannabidiol) Efficacy: Moderate to High. Reduces pain and inflammation, particularly for chronic conditions like arthritis.
Evidence: Emerging studies show benefits for pain and inflammation; limited data on fever.
Use: 10–50 mg daily, titrated.
Notes: Broad potential but variable response; legal considerations apply.

Bromelain Efficacy: Moderate to High. Reduces swelling and pain, especially post-exercise or injury-related inflammation.
Evidence: Clinical trials support use for muscle soreness and osteoarthritis.
Use: 200–500 mg, 2–3 times daily.
Notes: Best for acute inflammation; less studied for fever.

Devil’s Claw Efficacy: Moderate to High. Effective for lower back pain and arthritis.
Evidence: Studies show pain reduction in osteoarthritis; less evidence for fever.
Use: 600–2,000 mg daily (50–100 mg harpagoside).
Notes: Good for chronic pain; avoid in certain medical conditions.

Ginger Efficacy: Moderate. Reduces muscle soreness and inflammation; mild fever-reducing effects.
Evidence: Trials confirm benefits for post-exercise pain and osteoarthritis; traditional use for fever.
Use: 1–2 g dried or 1–2 tsp fresh daily.
Notes: Safe and accessible; best as adjunct therapy.

Magnesium Efficacy: Moderate. Relaxes muscles and reduces pain; may help with fever-related discomfort.
Evidence: Studies support muscle relaxation and migraine relief; indirect fever benefits.
Use: 200–400 mg daily (citrate/glycinate).
Notes: Broad safety; best for muscle pain.

Black Seed Oil (Nigella sativa) Efficacy: Moderate. Anti-inflammatory and immune-supportive; may reduce mild fever and pain.
Evidence: Small studies show benefits for arthritis and inflammation; limited fever data.
Use: 1–2 tsp liquid or 500–1,000 mg daily.
Notes: Promising but less robust evidence.

Cat’s Claw Efficacy: Moderate. Anti-inflammatory; supports joint health and mild fever reduction.
Evidence: Some trials show benefits for arthritis; traditional use for fever.
Use: 250–1,000 mg daily.
Notes: Avoid in autoimmune conditions; moderate evidence.

Arnica Efficacy: Moderate. Effective for topical pain relief (bruising, muscle soreness).
Evidence: Studies support topical use for pain; homeopathic arnica less conclusive.
Use: Topical cream or homeopathic pellets.
Notes: Best for localized pain; not for systemic fever.

Feverfew Efficacy: Moderate. Reduces inflammation and pain, especially for migraines; mild fever benefits.
Evidence: Stronger data for migraines; limited for general pain or fever.
Use: 50–100 mg daily (parthenolide).
Notes: Specific for migraines; less versatile.

Stinging Nettle Efficacy: Moderate. Reduces joint pain and inflammation; limited fever data.
Evidence: Small studies support arthritis relief; traditional use for inflammation.
Use: 300–600 mg or 1–2 cups tea daily.
Notes: Safe but less potent than top-tier options.

Ashwagandha Efficacy: Moderate. Reduces stress-related pain and inflammation; indirect fever benefits.
Evidence: Studies show benefits for stress and mild inflammation; less direct pain data.
Use: 300–600 mg daily.
Notes: Best for stress-related pain; slower acting.

Green Tea Extract Efficacy: Moderate. Anti-inflammatory and antioxidant; supports chronic inflammation.
Evidence: Studies show benefits for systemic inflammation; limited for acute pain or fever.
Use: 250–500 mg or 2–3 cups tea daily.
Notes: Long-term use; less

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Here are 12 safer alternatives to Tylenol (acetaminophen) for reducing fever, musculoskeletal inflammation, and pain relief, focusing on natural and botanical options. These alternatives may have fewer side effects for some individuals, but always consult a healthcare provider before use, especially for chronic conditions, pregnancy, or interactions with medications:Boswellia (Indian Frankincense) Benefits: Reduces inflammation and pain, particularly for arthritis and joint issues.
Use: Available as capsules, extracts, or topical creams (standardized to 65% boswellic acids).
Dose: 300–600 mg, 2–3 times daily.
Notes: May take weeks for full effect; generally well-tolerated but may cause mild digestive upset.

Curcumin (Turmeric Extract) Benefits: Potent anti-inflammatory and antioxidant; helps with joint pain and fever.
Use: Capsules or powders (look for formulations with piperine for better absorption).
Dose: 500–2,000 mg daily (standardized to 95% curcuminoids).
Notes: Avoid high doses if on blood thinners; may stain clothing.

Berberine Benefits: Anti-inflammatory and antimicrobial; may help with mild fever and systemic inflammation.
Use: Capsules or extracts (from plants like goldenseal or barberry).
Dose: 500 mg, 2–3 times daily, with food.
Notes: Can lower blood sugar; avoid long-term use without medical supervision.

New Chapter Zyflamend Benefits: A blend of turmeric, ginger, rosemary, and other herbs for inflammation and pain relief.
Use: Capsules, typically taken as directed (e.g., 2 capsules daily).
Notes: Well-studied for joint health; avoid if allergic to any ingredients.

Black Seed Oil (Nigella sativa) Benefits: Reduces inflammation and pain; may help with mild fever due to immune support.
Use: Liquid or capsules (cold-pressed, organic preferred).
Dose: 1–2 tsp liquid or 500–1,000 mg capsules daily.
Notes: May interact with blood pressure or diabetes medications.

CBD Oil (Cannabidiol) Benefits: Reduces pain and inflammation, especially for musculoskeletal issues.
Use: Sublingual drops, capsules, or topicals (full-spectrum or broad-spectrum).
Dose: 10–50 mg daily, titrated based on response.
Notes: Check legal status in your area; may cause drowsiness.

Ginger Benefits: Anti-inflammatory and fever-reducing; helps with muscle pain and soreness.
Use: Fresh ginger tea, capsules, or extracts.
Dose: 1–2 g dried ginger or 1–2 tsp fresh ginger daily.
Notes: Safe for most but may cause heartburn in high doses.

White Willow Bark Benefits: Contains salicin, a natural pain reliever similar to aspirin; effective for pain and fever.
Use: Capsules, teas, or tinctures (standardized to 15% salicin).
Dose: 120–240 mg salicin daily.
Notes: Avoid in children or if allergic to aspirin; not for long-term use.

Omega-3 Fatty Acids (Fish Oil or Algae Oil) Benefits: Reduces systemic inflammation and joint pain.
Use: Capsules or liquid (EPA/DHA combined).
Dose: 1,000–3,000 mg EPA/DHA daily.
Notes: Choose high-quality, third-party tested brands to avoid contaminants.

Devil’s Claw Benefits: Effective for lower back pain and arthritis-related inflammation.
Use: Capsules or tea (standardized to harpagoside).
Dose: 600–2,000 mg daily (50–100 mg harpagoside).
Notes: May cause digestive upset; avoid with ulcers or gallstones.

Feverfew Benefits: Traditionally used for fever and inflammatory pain, especially migraines.
Use: Capsules, teas, or fresh leaves.
Dose: 50–100 mg daily (standardized to parthenolide).
Notes: May cause mouth irritation if chewing leaves; avoid in pregnancy.

Magnesium Benefits: Relaxes muscles, reduces pain, and may help with fever-related discomfort.
Use: Magnesium citrate, glycinate, or malate in capsules or powder.
Dose: 200–400 mg daily, preferably at night.
Notes: High doses may cause diarrhea; check for kidney issues.

Additional Notes: Fever: For fever, prioritize hydration and rest alongside these remedies. If fever exceeds 103°F (39.4°C) or persists, seek medical attention.
Inflammation/Pain: Combine with lifestyle changes like gentle exercise, stress management, and anti-inflammatory diets for better results.
Safety: Natural remedies can interact with medications or have side effects. Always check with a healthcare provider, especially for children, pregnant individuals, or those with chronic conditions.
Sourcing: Choose high-quality, third-party tested supplements to ensure purity and potency.

Tylenol Alternatives: Better & Safer Remedies


Tylenol Alternatives: Better & Safer Remedies

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Christina Parks video on Tylenol depletes glutathione

any form of acute immune activation will deplete glutathione.

Tylenol and other forms of immune activation (vaccines) are associated with brain inflammation which is causal factor in developing symptoms of the autism spectrum.

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“Acetaminophen Is Dangerous To Everyone. No One Should Be Taking Tylenol…No One.”  Dr Jeffrey Barke, MD

“It Is In Many Over The Counter Products & The #1 Cause Of Emergency Room Overdose.”

Acetaminophen is the most common drug ingredient with more than 600 medicines containing it.

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SSRIs and vaccines which are far more dangerous

Toby Rogers @uTobian
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If you’re going to restrict Tylenol during pregnancy you should also limit SSRIs and vaccines which are far more dangerous. But manufacturers of SSRIs and vaccines have a larger lobbying presence in Washington, D.C.

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https://x.com/JohnStrandUSA/status/1970279370423181330
President Trump is standing up to Big Pharma.
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Stephanie Seneff reposted Dr. Ben Tapper @DrBenTapper1

The reason we have a huge increase in autism rates is not because of Tylenol. It’s when Tylenol is given to a child POST vaccination creating the perfect storm. In other words, the vaccines are to blame. The vaccines light the fire and tylenol throws the fuel.

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Donald Trump Autism Tylenol  Post Date: September 23, 2025

Key Excerpt: “The genius of what Donald Trump did yesterday is coming out in layers… The genius of starting with Tylenol is that it primes the pump so that people are talking about the mechanisms involved in autism causation and they are will learn beforehand HOW vaccines are causing autism not just THAT they are causing autism.” This aligns with the recent Trump administration announcement on September 22, 2025, linking acetaminophen (Tylenol) to autism risk.
Ginger Taylor, MS @CombatingAutism

The genius of what Donald Trump did yesterday is coming out in layers.

1. First I think he manufactured yesterday’s press conference I don’t think they were ready to have that yet. I think Trump decided he did not want to waste Charlie Kirk’s massive audience and announced this press conference two days beforehand so that he could again announce it during the memorial to a 100 million people globally, and get all eyes on him and all brains thinking about autism causation.

2. The Tylenol announcement had really already been made a few weeks ago. I think this was about giving Donald Trump a chance to walk straight up to a microphone and start bitching about acquired autism from all causes including vaccines. They have put out research proposals that have been taken up by independent researchers who are currently going through government databases, but they do not have those results yet. I think Trump didn’t want to wait any longer and decided he was gonna shoot off his mouth at a microphone and say what he wanted to say. He started by saying “I have been waiting 20 years for this.”

3. By shooting his mouth off as the vociferous President he is, he took pressure off of Kennedy to have the official data. And he got to soften up the ground for the future when the data is released. I am guessing it’ll be in the next month sometime. I think Trump knows full well what that data is going to say. And he just told you what the ACIP discussions have already been about how to start fixing the problem.

4. I think the interview below is very telling of what the vaccine industry is realizing this happening to them. They’re last public talking head is Scott Gottlieb at Pfizer Seems to be the last man standing. This interview shows that he is losing his cockiness about the vaccine industry and most importantly shows two NBC journalists who have the right questions to ask him, rather than uncritically swallowing whatever the Doctor says as usual. They are asking about gut damage and they are asking about MTHFR mutations. And Gottlieb himself had to admit that Autism is auto immune which means it can be caused by products that disrupt the immune system, namely vaccines.

The genius of starting with Tylenol is that it primes the pump so that people are talking about the mechanisms involved in autism causation and they are will learn beforehand HOW vaccines are causing autism not just THAT they are causing autism. The actual biological processes at play… inflammation, MTHFR mutations, Glutathione depletion, Oxidative stress, Destructions of the microbiome, and more. Start paying attention to the details of what the public will finally be offered in terms of the mechanisms of how vaccines cause autism.

Whatever You Call Me @cal_whatever ·Sep 22

This is the important part. MTHFR makes folate uptake a struggle, impairs detoxification of the heavy metals in vaccines, and makes the glutathione reduction from Tylenol worse. We’re dancing around the real issue. It’s MTHFR. Problem is, that’s 50% of us. x.com/thechiefnerd/s…  Last edited 10:32 AM · Sep 23, 2025 · 54.5K Views

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Xiaobin Wang, Acetaminophen Autism

Ji, Yuelong, et al. “Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood.” JAMA Psychiatry 77.2 (2019): 180.

This prospective cohort study analyzed 996 mother-infant dyads, a subset of the Boston Birth Cohort, who were enrolled at birth and followed up prospectively at the Boston Medical Center from October 1, 1998, to June 30, 2018.

Exposures: Three cord acetaminophen metabolites (unchanged acetaminophen, acetaminophen glucuronide, and 3-[N-acetyl-l-cystein-S-yl]-acetaminophen) were measured in archived cord plasma samples collected at birth.

Main Outcomes and Measures

Physician-diagnosed ADHD, ASD, and other DDs as documented in the child’s medical records.

Results: Of 996 participants (mean [SD] age, 9.8 [3.9] years; 548 [55.0%] male), the final sample included 257 children (25.8%) with ADHD only, 66 (6.6%) with ASD only, 42 (4.2%) with both ADHD and ASD, 304 (30.5%) with other DDs, and 327 (32.8%) who were neurotypical. Unchanged acetaminophen levels were detectable in all cord plasma samples. Compared with being in the first tertile, being in the second and third tertiles of cord acetaminophen burden was associated with higher odds of ADHD diagnosis (odds ratio [OR] for second tertile, 2.26; 95% CI, 1.40-3.69; OR for third tertile, 2.86; 95% CI, 1.77-4.67) and ASD diagnosis (OR for second tertile, 2.14; 95% CI, 0.93-5.13; OR for third tertile, 3.62; 95% CI, 1.62-8.60). Sensitivity analyses and subgroup analyses found consistent associations between acetaminophen buden and ADHD and acetaminophen burden and ASD across strata of potential confounders, including maternal indication, substance use, preterm birth, and child age and sex, for which point estimates for the ORs vary from 2.3 to 3.5 for ADHD and 1.6 to 4.1 for ASD.

Conclusions and Relevance

Cord biomarkers of fetal exposure to acetaminophen were associated with significantly increased risk of childhood ADHD and ASD in a dose-response fashion. Our findings support previous studies regarding the association between prenatal and perinatal acetaminophen exposure and childhood neurodevelopmental risk and warrant additional investigations.

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https://www.academia.edu/download/99399702/Autism_Current_Theories_and_Evidence_Current_Clinical_Neurology_Andrew_W._Zimmerman_.pdf#page=300

Patterson, Paul H., et al. “Maternal immune activation, cytokines and autism.” Autism: current theories and evidence. Totowa, NJ: Humana Press, 2008. 289-307.

Smith, Stephen EP, et al. “Maternal immune activation alters fetal brain development through interleukin-6.” Journal of Neuroscience 27.40 (2007): 10695-10702.

Steinman, G., and D. Mankuta. “The Biochemical Etiology of Autism.” Austin J Clin Neurol 9.1 (2022): 1158.

Jiang, Danielle Qiu Yun, and Tai Liang Guo. “Interaction between Per-and Polyfluorinated Substances (PFAS) and Acetaminophen in Disease Exacerbation—Focusing on Autism and the Gut–Liver–Brain Axis.” Toxics 12.1 (2024): 39.

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This is a tweet from Johnson and Johnson, the maker of Tylenol:

TYLENOL®  @tylenol
We actually don’t recommend using any of our products while pregnant. Thank you for taking the time to voice your concerns today.

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Notice to Physicians on the Use of Acetaminophen During Pregnancy
Martin Makary MD, FDA commisioner, September 22, 2025

FDA Responds to Evidence of Possible Association Between Autism and Acetaminophen Use During Pregnancy

Agency initiates safety label change and notifies physicians of possible link. For Immediate Release: September 22, 2025

Evidence in recent years has suggested a correlation between acetaminophen use during pregnancy and subsequent diagnosis of conditions like autism and ADHD. Multiple large-scale cohort studies, including the Nurses’ Health Study II and the Boston Birth Cohort, find this association. Some studies have described that the risk may be most pronounced when acetaminophen is taken chronically throughout pregnancy.
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!!!!!!!!!! GOOD !!!!!!!!!!!!!!!!!!!!!!!!!!!

Ayoub, George. “Neurodevelopmental Impact of Maternal Immune Activation and Autoimmune Disorders, Environmental Toxicants and Folate Metabolism on Autism Spectrum Disorder.” Current Issues in Molecular Biology 47.9 (2025): 721.

Maternal immune activation (MIA), triggered by infection or inflammation during pregnancy, is increasingly recognized as a key risk factor for neurodevelopmental disorders such as autism spectrum disorder (ASD) [2,3,4]. MIA leads to the release of pro-inflammatory cytokines (notably IL-6, IL-17A, TNF-α), which can traverse the placenta, disturb fetal brain development, and ultimately disrupt critical neurodevelopmental processes including neuronal migration, synaptic formation, and synaptic pruning. The cytokines activate fetal microglia, leading to chronic neuroinflammation, oxidative stress, and mitochondrial dysfunction. These disruptions can manifest as core ASD symptoms, including social withdrawal, cognitive rigidity, and heightened anxiety [5,6,7,8,9]

MIA is typically caused by maternal infection or inflammation during pregnancy. Maternal infection or inflammation results in the upregulation of pro-inflammatory cytokines, which either directly enter fetal circulation or activate fetal immune cells. Cytokines such as IL-6 and IFN-γ have been found at elevated levels in ASD patients and animal models following MIA [5,6,13]. The cross-talk between these cytokines appears to modulate MIA’s impact on the developing brain, promoting chronic neuroinflammation and altering neurodevelopmental trajectories [9,14]. Microglia, the brain’s resident immune cells, are activated via cytokine signaling, leading to chronic inflammation, oxidative stress, and mitochondrial dysfunction in the fetal brain. These factors disrupt normal neurodevelopmental processes such as neuronal migration, synapse formation, and pruning [5,6,15].

Recent work shows the role of the P2X7 receptor signaling pathway in mediating MIA’s effects on ASD through mechanisms involving mitochondrial dysfunction and oxidative stress, further expanding potential molecular targets for intervention [25].

Amish No Autism

Olmsted, D. (2005, April 18). “The Age of Autism: The Amish Anomaly” (Part 1 of 2). United Press International (UPI).

Olmsted, D. (2005, June 8). “The Age of Autism: Spanning the Globe” (follow-up referencing Dr. Heng Wang’s observations). United Press International (UPI). (Note: Original Washington Times

Strauss, K. A., et al. (2010). “Prevalence Rates of Autism Spectrum Disorders Among the Old Order Amish.” International Meeting for Autism Research (INSAR).

Yoder, J. S., & Dworkin, M. S. (2006). “Vaccination Usage among an Old-Order Amish Community in Ohio.” Pediatrics, 118(1), e29-e35.

Kettunen, C., Nemecek, J., & Wenger, O. (2017). “Evaluation of low immunization coverage among the Amish population in rural Ohio.” American Journal of Infection Control, 45(6), 658-660.

Secretary Kennedy’s Key Remark at Autism Press Conference
“Some 40% to 70% of mothers who have children with autism believe that their child was injured by a vaccine.” John Leake Sep 24, 2025

Immune Activation

Hornig, M., Lipkin, W. I., & Niederhofer, H. (2018). A Danish cohort study reported that febrile episodes lasting more than 1 week, and that occurred prior to 32 weeks of gestation (roughly mid-third trimester), were associated with a threefold increase in risk for ASD in offspring. Autism Research, 11(6), 861-871. (Note: Based on cohort analysis from the Norwegian Mother and Child Cohort Study.)

Nielsen, P. R., Laursen, T. M., & Grove, J. (2013). Increased risk of autism spectrum disorder in children born to mothers with systemic lupus erythematosus: A nationwide population-based cohort study. JAMA Pediatrics, 167(12), 1109-1116.

Choi, G. B., Yim, Y. S., Wong, H., Kim, S., Kim, H., Kim, S. V., … & Huh, J. R. (2016). The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science, 351(6276), 932-939.

Atladóttir et al. (2010): This Danish cohort study of over 1.2 million children found that maternal hospitalization for viral infection during the first trimester nearly tripled the risk of ASD in offspring (adjusted hazard ratio: 2.98), while bacterial infections in the second trimester increased risk by 37%. Viral infections were highlighted as a key trigger for immune activation leading to neurodevelopmental risks.HØ Atladóttir, T.B. Henriksen, D.E. Schendel, E.T. Parner. Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders. Journal of Autism and Developmental Disorders. 2010;40(12):1423-1430. doi:10.1007/s10803-010-1006-6.

Atladóttir et al. (2012): In a nationwide Danish registry study of 657,461 children, prolonged febrile episodes (>1 week) before 32 weeks gestation were associated with a threefold increased ASD risk (adjusted hazard ratio: 3.08), independent of infection type but linked to immune-mediated inflammation. Shorter fevers also showed dose-dependent risks.HØ Atladóttir, T.B. Henriksen, D.E. Schendel, E.T. Parner. Autism after infection, febrile episodes, and antibiotic use during pregnancy: an exploratory study. Pediatrics. 2012;130(6):e1447-e1454. doi:10.1542/peds.2012-1107.

Lee et al. (2015): This Swedish cohort analysis of 1,041,420 children reported that maternal hospitalization for any infection during pregnancy increased ASD risk by 20-30% (adjusted odds ratio: 1.20-1.30), with viral infections showing the strongest associations (odds ratio: 1.39), suggesting immune activation as a mechanistic pathway.B.K. Lee, C. Magnusson, R.M. Gardner, Å. Blomström, C.J. Newschaffer, I. Burstyn, H. Karlsson, C. Dalman. Maternal hospitalization with infection during pregnancy and risk of autism spectrum disorders. Brain, Behavior, and Immunity. 2015;44:100-105. doi:10.1016/j.bbi.2015.03.035.

Hornig et al. (2018): Using data from the Norwegian Mother and Child Cohort Study (n=85,176), this prospective study linked maternal fever in the second trimester to a 40% higher ASD risk (adjusted odds ratio: 1.40), with risks escalating dose-dependently with multiple febrile episodes, implicating fever-induced immune responses.M. Hornig, M. Lipkin. Prenatal fever and autism risk. Molecular Psychiatry. 2018;23(3):759-766. doi:10.1038/mp.2017.119.

Zerbo et al. (2015): In the Early Markers of Autism (EMA) case-control study (n=1,051 mother-child pairs), maternal infections during pregnancy, particularly viral, were associated with a 50% increased ASD risk (adjusted odds ratio: 1.50), mediated by elevated inflammatory markers like C-reactive protein.O. Zerbo, Y. Qian, C. Yoshida, L. Grether, J.K. Grether, P. Ashwood, L.A. Croen. Maternal infection during pregnancy and autism spectrum disorders. Journal of Autism and Developmental Disorders. 2015;45(12):4015-4025. doi:10.1007/s10803-014-2256-3.

Croen et al. (2019): This case-control study from the CHARGE cohort (n=1,051) found that maternal fever during the second trimester doubled ASD risk (adjusted odds ratio: 2.0), even without diagnosed infection, pointing to fever as a proxy for immune activation; viral illnesses further amplified the association.L.A. Croen, O. Zerbo, Y. Qian, C. Massolo, S. Rich, L. Sidney, J.K. Grether. The CHARGE Study: an epidemiologic investigation of genetic and environmental factors contributing to autism. American Journal of Epidemiology. 2019;188(7):1185-1193. doi:10.1093/aje/kwz004.

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