COX2 Inhibitor Celecoxib As Anti-Cancer Drug

Bernard 2008 COX2 Inhibitors for Hematologic Malignancy

COX2 Inhibitors As Anti-Cancer Agents The COX2 (Cyclo-Oxygenase) pathway is upregulated in cancer, and COX2 inhibitors (celecoxib) can inhibit cell proliferation, tumor¬† invasiveness, and angiogenesis.¬† They can also overcome apoptosis resistance by BCL2, and overcome P-glycoprotein/MDR drug resistance, as well … Continue reading